ICD-10-CM code · FY2027
E88 Other and unspecified metabolic disorders
Header codeNot billable: use one of the 24 billable codes below
About E88
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Coding notes for E88
Excludes1 Not coded here: never report these together with this code (use the code given instead).
- histiocytosis X (chronic) (C96.6)
Use additional code Add a second code for the detail named here.
- codes for associated conditions
Block E70-E88 notes (apply to every code in it)
Excludes1 Not coded here: never report these together with this code (use the code given instead).
Excludes2 Not part of this condition, but a patient can have both: report both codes when both apply.
- Ehlers-Danlos syndromes (Q79.6-)
Chapter 4 notes (apply to every code in it)
Note
- All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
Codes under E88 29
- E88.0 Disorders of plasma-protein metabolism, not elsewhere classifiedHeader
- E88.01 Alpha-1-antitrypsin deficiencyBillable
- E88.02 Plasminogen deficiencyBillable
- E88.09 Other disorders of plasma-protein metabolism, not elsewhere classifiedBillable
- E88.1 Lipodystrophy, not elsewhere classifiedHeader
- E88.10 Lipodystrophy, unspecifiedBillable
- E88.11 Partial lipodystrophyBillable
- E88.12 Generalized lipodystrophyBillable
- E88.13 Localized lipodystrophyBillable
- E88.14 HIV-associated lipodystrophyBillable
- E88.19 Other lipodystrophy, not elsewhere classifiedBillable
- E88.2 Lipomatosis, not elsewhere classifiedBillable
- E88.3 Tumor lysis syndromeBillable
- E88.4 Mitochondrial metabolism disordersHeader
- E88.40 Mitochondrial metabolism disorder, unspecifiedBillable
- E88.41 MELAS syndromeBillable
- E88.42 MERRF syndromeBillable
- E88.43 Disorders of mitochondrial tRNA synthetasesBillable
- E88.49 Other mitochondrial metabolism disordersBillable
- E88.8 Other specified metabolic disordersHeader
- E88.81 Metabolic syndrome and other insulin resistanceHeader
- E88.810 Metabolic syndromeBillable
- E88.811 Insulin resistance syndrome, Type ABillable
- E88.818 Other insulin resistanceBillable
- E88.819 Insulin resistance, unspecifiedBillable
- E88.82 Obesity due to disruption of MC4R pathwayBillable
- E88.89 Other specified metabolic disordersBillable
- E88.9 Metabolic disorder, unspecifiedBillable
- E88.A Wasting disease (syndrome) due to underlying conditionBillable
Other categories in E70-E88
- E70 Disorders of aromatic amino-acid metabolismHeader
- E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolismHeader
- E72 Other disorders of amino-acid metabolismHeader
- E73 Lactose intoleranceHeader
- E74 Other disorders of carbohydrate metabolismHeader
- E75 Disorders of sphingolipid metabolism and other lipid storage disordersHeader
- E76 Disorders of glycosaminoglycan metabolismHeader
- E77 Disorders of glycoprotein metabolismHeader
- E78 Disorders of lipoprotein metabolism and other lipidemiasHeader
- E79 Disorders of purine and pyrimidine metabolismHeader
- E80 Disorders of porphyrin and bilirubin metabolismHeader
- E83 Disorders of mineral metabolismHeader
- E84 Cystic fibrosisHeader
- E85 AmyloidosisHeader
- E86 Volume depletionHeader
- E87 Other disorders of fluid, electrolyte and acid-base balanceHeader
Latest research on metabolic syndrome
- Low-dose combined hormonal contraceptives may be effective in managing symptoms of polycystic ovarian syndrome without increasing the prevalence of metabolic syndrome
- Probiotic use may decrease risk factors for metabolic syndrome
- Time-restricted eating may improve glycemic control in patients with metabolic syndrome
- There may be an association between anxiety and metabolic syndrome
- Christian Orthodox Church fasting may improve metabolic syndrome risk factors
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See 2MM+ plansICD-10-CM FY2027 code set, as published by the CDC National Center for Health Statistics (NCHS) and CMS, effective October 1, 2026 to September 30, 2027. Codes, titles and notes are shown as published. Check payer rules and the official guidelines before billing. This page is not medical advice.
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