• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • 2MM Podcast
  • Write for us
  • Contact Us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Infectious Disease

Low transmission in household contacts of patients with MERS-CoV

byAndrew Cheung, MD MBAandMatthew Sibbald, MD, PhD
August 28, 2014
in Infectious Disease, Pulmonology
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

1. Of the 280 household contacts linked with 26 index cases of Middle East respiratory syndrome coronavirus (MERS-CoV) infection, 12 probable cases of secondary transmission were identified. 

2. The risk of secondary transmission likely differs in different situations; for example, transmission may be higher in nosocomial outbreaks.

Evidence Rating Level: 4 (Poor) 

Study Rundown: MERS-CoV was first identified in Saudi Arabia in 2012. There are over 800 laboratory-confirmed cases, with 288 fatalities as of July 2014. While much effort has been devoted to better characterizing MERS-CoV, there is still a limited understanding of its epidemiologic features. The purpose of this study was to assess the rate of silent or subclinical infection after exposure to cases of MERS-CoV infection. This cross-sectional study tested 280 household contacts of 26 index patients. Using reverse-transcriptase-polymerase-chain-reaction (RT-PCR) and serologic analysis, 12 probable cases of secondary transmission were identified. Notably, the rates of secondary transmission may be much different in other circumstances such as nosocomial outbreaks.

Click to read the study, published today in NEJM

Relevant Reading: Hospital outbreak of Middle East Respiratory Syndrome coronavirus

RELATED REPORTS

2 Minute Medicine Rewind August 25 – September 1, 2014

First report of acute MERS-CoV infection associated with adverse pregnancy outcome

High mortality rates reported in ill patients with MERS-CoV

In-Depth [cross-sectional study]: This cross-sectional study examined household contacts of 26 index patients with clinically-apparent MERS-CoV infections. Index patients were identified as patients who were hospitalized with bilateral pneumonia and had MERS-CoV detected in respiratory samples through RT-PCR. All individuals living with these index patients participated in this investigation by providing pharyngeal swab specimens and primary serum samples. A small subset of the population also provided follow-up serum samples for further analysis. A total of 12 probable cases of secondary transmission were identified (4%; 95% confidence interval, 2 to 7). Of these, 7 were found to be positive through RT-PCR on pharyngeal swabs while 5 cases were identified through serologic analysis (i.e., recombinant ELISA and immunofluorescence assays).

Image: PD

©2012-2014 2minutemedicine.com. All rights reserved. No works may be reproduced without expressed written consent from 2minutemedicine.com. Disclaimer: We present factual information directly from peer reviewed medical journals. No post should be construed as medical advice and is not intended as such by the authors, editors, staff or by 2minutemedicine.com. PLEASE SEE A HEALTHCARE PROVIDER IN YOUR AREA IF YOU SEEK MEDICAL ADVICE OF ANY SORT.

Tags: MERS-CoV
Previous Post

Erythropoietin linked with reduced risk of brain injury in preterm infants

Next Post

Higher cardiovascular mortality in low- and middle-income countries [PURE study]

RelatedReports

2 Minute Medicine Rewind August 25 – September 1, 2014
Cardiology

2 Minute Medicine Rewind August 25 – September 1, 2014

September 1, 2014
Antepartum and intrapartum events both linked to neonatal HIE
Obstetrics

First report of acute MERS-CoV infection associated with adverse pregnancy outcome

February 16, 2014
High mortality rates reported in ill patients with MERS-CoV
Chronic Disease

High mortality rates reported in ill patients with MERS-CoV

May 2, 2014
Soaring rates of peripheral artery disease, now over 200 million cases worldwide
Cardiology

2 Minute Medicine Rewind August 19 – August 25, 2013

August 26, 2013
Next Post
Successful regional implementation of pediatric chest pain algorithm

Higher cardiovascular mortality in low- and middle-income countries [PURE study]

Macitentan better than placebo for preventing progression of pulmonary arterial hypertension [SERAPHIN Trial]

Collaborative care model reduces depression in lung cancer patients [SMaRT Oncology-3 Trial]

High dose antidepressants may increase self-harm risk among children, young adults

Most cancer patients may not receive adequate treatment for comorbid depression

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • The Scan by 2 Minute Medicine®: Celebrity diagnoses spur screenings, athlete mental-health push, reality-TV heart lesson, and a sitcom PSA wave
  • Early acetaminophen use reduces mortality risk in patients with sepsis-associated encephalopathy
  • Structured Exercise after Adjuvant Chemotherapy for Colon Cancer
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
No Result
View All Result

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.