• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Cardiology

No benefit with preoperative beta-blocker use in coronary bypass surgery

byGautam GadeyandJames Jiang
June 17, 2014
in Cardiology, Surgery
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

1. In a retrospective analysis of patients who had never had a myocardial infarction, preoperative b-blocker use was not associated with any difference in rates of mortality, stroke, ventilation durations, renal failure, or sternal wound infection. 

2. Preoperative b-blocker use was associated with higher rates of new-onset atrial fibrillation. 

Evidence Rating Level: 2 (Good)            

Study Rundown: Retrospective analyses in the 1990s seemed to suggest benefits of preoperative b-blocker use.  Preoperative b-blocker use in CABG patients has since become a quality standard in the UK, affecting the reimbursement levels of the hospitals and surgeons.  However, more recent meta-analyses do not seem to reveal the same consistent benefits.  In addition, the DECREASE family of trials has been delegitimized due to scientific misconduct.

The authors of this study only included nonemergency, isolated CABG patients and also excluded patients who had a myocardial infarction within 21 days of the operation.  The study revealed that rates of operative mortality, permanent stroke, prolonged ventilation, reoperation, renal failure, deep sternal wound infection were similar among both groups.  Interestingly, patients with preoperative b-blocker use had a significantly higher rate of new-onset postoperative atrial fibrillation.  Strengths of the study include the large patient population included.  Unfortunately, although b-blocker use for this purpose has become a very controversial topic, there have not been any large randomized prospective trials addressing this topic.

Click to read the study ,published today in JAMA Internal Medicine

Relevant Reading: Perioperative beta-blockers for preventing surgery-related mortality and morbidity: a systematic review and meta-analysis

RELATED REPORTS

Improved mortality rates for myocardial infarction, stroke, and pulmonary embolism in patients receiving dialysis between 1998 to 2015

Ophthalmologic procedures are not associated with increased risk for acute myocardial infarction

Clinically important troponin I threshold for mortality after cardiac surgery

In-Depth [retrospective cohort]: In this study, a retrospective analysis based on data in the Society of Thoracic Surgeons National Adult Cardiac database was performed.  506,110 patients who were older than 18 years of age, undergoing non-emergent CABG surgery and had not experienced a myocardial infarction in the prior 21 days met inclusion criteria.

Over 86% of patients had received b-blockers within 24 hours of surgery.  No significant difference between the groups was found in rates of operative mortality (OR, 0.96 [95% CI, 0.87-1.06]), permanent stroke, prolonged ventilation, any reoperation, renal failure, or deep sternal wound infection.  New-onset atrial fibrillation was higher in the group receiving preoperative b-blockers (OR, 1.09 [95% CI, 1.06-1.12]).

Image: PD 

©2012-2014 2minutemedicine.com. All rights reserved. No works may be reproduced without expressed written consent from 2minutemedicine.com. Disclaimer: We present factual information directly from peer reviewed medical journals. No post should be construed as medical advice and is not intended as such by the authors, editors, staff or by 2minutemedicine.com. PLEASE SEE A HEALTHCARE PROVIDER IN YOUR AREA IF YOU SEEK MEDICAL ADVICE OF ANY SORT.  

Tags: beta blockerCABGmyocardial infarction
Previous Post

Low-strength evidence for hepatocellular carcinoma screening in liver disease

Next Post

No link between TNF-a inhibitor use and cancer in inflammatory bowel disease

RelatedReports

Fish oil and aspirin did not reduce arteriovenous fistula failure: The FAVOURED trail
Cardiology

Improved mortality rates for myocardial infarction, stroke, and pulmonary embolism in patients receiving dialysis between 1998 to 2015

April 22, 2022
Nonpowder gun-related pediatric eye injuries on the rise
Cardiology

Ophthalmologic procedures are not associated with increased risk for acute myocardial infarction

April 22, 2022
30-Day mortality decreased in UK pediatric cardiac surgery from 2000-2010
Cardiology

Clinically important troponin I threshold for mortality after cardiac surgery

March 8, 2022
StudyGraphics

#VisualAbstract: Effectiveness of sacubitril-valsartan in post-myocardial infarction management compared to ramipril

February 10, 2022
Next Post
Thalidomide may be effective in refractory pediatric Crohn’s disease

No link between TNF-a inhibitor use and cancer in inflammatory bowel disease

Hypercortisolemia in ICU patients is due to reduced cortisol metabolism, not increased production

Affordable Care Act: Improved health, lower costs in youth with dependent coverage

Fibrinolysis for pulmonary embolism may prevent hemodynamic collapse [PEITHO trial]

Thrombolysis for pulmonary embolism may benefit younger patients, harm older patients

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

Get 2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Wellness Check: Mental Health
  • #VisualAbstract: Addition of elotuzumab to lenalidomide and dexamethasone did not significantly improve survival outcomes in newly diagnosed, transplant-ineligible multiple myeloma
  • #VisualAbstract: Pretreatment with radiotherapy and two cycles of concurrent cisplatin may reduce toxicity in locally advanced nasopharyngeal carcinoma
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.