Tag: myocardial infarction

1. Risk of cardiovascular death, myocardial infarction, stroke, and revascularization was lower in the fixed-dose combination pill group compared to control. 2. Fixed-dose combination strategies with aspirin resulted in greater reductions in mortality compared to without aspirin. Evidence Rating Level: 1 (Excellent) Study Rundown: Cardiovascular disease is among the leading causes of...

1. Risk of acute myocardial infarction and ischemic stroke was increased during the first two weeks following a COVID-19 infection compared to the general population. 2. The risk of developing acute myocardial infarction and ischemic stroke decreased in weeks 3-4 following a COVID-19 infection compared to the first two weeks. Evidence...

1. Compared to patients only receiving rate-control treatment, those who received rhythm-control treatment within one year of diagnosis of atrial fibrillation had a lower risk of adverse cardiovascular outcomes. 2. This association was not seen if the treatment was initiated over one year after the diagnosis of atrial fibrillation. Evidence Rating...

1. Biomarkers quantifying endothelial dysfunction, microvascular dysfunction, and/or hemodynamic stress provided modest diagnostic performance in the early discrimination of type 2 myocardial infarction (T2MI) from type 1 myocardial infarction (T1MI). 2. Given their limited clinical significance, clinical parameters and diagnostic investigations including coronary angiography and/or noninvasive functional or anatomic testing...

1. Patients without standard modifiable cardiovascular risk factors (SMuRFs) had a significantly higher all-cause mortality at 30 days after first presentation of STEMI. 2. Patients without SMuRFs were significantly less likely to receive statins, ACEIs, ARBs, or beta-blockers at discharge.  Evidence Rating Level: 2 (Good) Study Rundown: Standard modifiable cardiovascular risk factors...

1. The PRAISE score showed accurate discriminative capabilities for the prediction of all-cause death, acute myocardial infarction, and major bleeding after an acute coronary syndrome. 2. Compared with low risk stratification, a high-risk PRAISE score was associated with a 58.8-times increase in death, 27.7-times increase in myocardial infarction, and a...

1. There was no significant difference in periprocedural myonecrosis between ticagrelor and clopidogrel among patients undergoing high-risk elective PCI. 2. Ticagrelor treatment was associated with an increased rate of minor bleeding at 30 days post-operation. Evidence Rating Level: 1 (Excellent) Study Rundown: Percutaneous coronary intervention (PCI) provides a safe therapeutic option for patients with...

1. Increased levels of circulating ACE2 were associated with greater risk of cardiovascular and non-cardiovascular death, heart failure, myocardial infarction, stroke, and diabetes. 2. Compared to other clinical risk factors such as diabetes, body-mass index, smoking status, non-HDL cholesterol, and systolic blood pressure, plasma ACE2 was the strongest predictor...

1. The proportion of out of hospital cardiac arrests (OHCAs) within all acute myocardial infarction (AMI) hospital admissions was higher at the start of the COVID-19 pandemic compared to before, by a difference of 2.0%. 2. The in-hospital mortality rate for OHCAs during COVID-19 was higher than before, by a...

1. In this prospective modeling study of elderly adults who were hospitalized for acute myocardial infarction, the novel SILVER-AMI model appeared well-calibrated and had improved discrimination when compared the the commonly-used GRACE model. 2. Unique to the SILVER-AMI, several functional impairments were found to be independently associated with mortality and...