Tag: myocardial infarction

1. In this prospective modeling study of elderly adults who were hospitalized for acute myocardial infarction, the novel SILVER-AMI model appeared well-calibrated and had improved discrimination when compared the the commonly-used GRACE model. 2. Unique to the SILVER-AMI, several functional impairments were found to be independently associated with mortality and...

1. Bleeding after percutaneous coronary intervention (PCI) was more common in women, but the effect of two antiplatelet strategies on death and new Q-wave myocardial infarction following PCI did not differ between men and women. Evidence Rating Level: 1 (Excellent) Percutaneous coronary intervention (PCI) is a highly effective treatment in coronary...

Bleeding after percutaneous coronary intervention (PCI) was more common in women, but the effect of two antiplatelet strategies on death and new Q-wave myocardial infarction following PCI did not differ between men and women. Evidence Rating Level: 1 (Excellent) Percutaneous coronary intervention (PCI) is a highly effective treatment in coronary...

Association of Sex With Outcomes in Patients Undergoing Percutaneous Coronary Intervention: A Subgroup Analysis of the GLOBAL LEADERS Randomized Clinical Trial 1. Bleeding after percutaneous coronary intervention (PCI) was more common in women, but the effect of two antiplatelet strategies on death and new Q-wave myocardial infarction following PCI did...

1. Patients with obesity undergoing percutaneous coronary intervention are typically younger with more cardiovascular risk factors, but may be less likely to experience procedural complications, short-term and long-term adverse outcomes, with the exception of patients considered extremely obese Evidence Rating Level: 2 (Good) It has been well established that obesity is...

PD-1 blockade in advanced adrenocortical carcinoma 1. Pembrolizumab may provide clinically meaningful anti-tumor activity in the setting of adrenocortical carcinoma, particularly in tumors characterized by microsatellite instability and/or mismatch repair  Evidence Rating Level: 2 (Good) Adrenocortical carcinomas (ACC) are rare and typically carry a poor prognosis, with the majority of patients presenting...

Oxaliplatin-Based Adjuvant Chemotherapy for Rectal Cancer After Preoperative Chemoradiotherapy (ADORE): Long-Term Results of a Randomized Controlled Trial 1. Adjuvant FOLFOX improves disease-free survival in patients with pathologic Stage II or III rectal cancer after upfront surgery and preoperative chemoradiotherapy, but is associated with a higher rate of adverse events. Evidence...

The risk of adverse cardiovascular outcomes in patients hospitalized with acute coronary syndrome (ACS) is highest in elderly patients. Although recent clinical trials have shown that high-intensity statin therapy significantly reduces adverse cardiovascular events for patients with established coronary heart disease, its use in elderly individuals remains controversial. As...

1. In this cross-sectional cohort study of older adults in Iceland, MRI findings of myocardial infarction was associated with coincident MRI findings of cerebral infarction. 2. Patients with embolic patterns of cerebral infarction, without a clear source, had a higher likelihood of unrecognized myocardial infarction diagnosed by MRI. Evidence Rating Level:...

The following study summary is an excerpt from the book 2 Minute Medicine’s The Classics in Radiology: Summaries of Clinically Relevant & Recent Landmark Studies, 1e (The Classics Series). 1. In patients presenting to the emergency department with acute chest pain, evaluation with computed tomographic coronary angiography (CTCA) led to significantly...