Tag: beta blocker

1. In patients with stable heart failure, adrenergic co-transmitter neuropeptide Y (NPY) levels can identify patients at risk of adverse outcomes related to hyperadrenergic activation Evidence Rating Level: 2 (Good) The adrenergic co-transmitter neuropeptide Y (NPY) is one of the neurotransmitters released by cardiac sympathetic nerve terminals, and may represent an...

1. In this double-blind randomized trial of COPD patients without previous indication for beta blocker therapy, treatment with extended-release beta-blockers failed to generate improved health outcomes versus placebo. No significant between-group difference was found in the median time until the first exacerbation of COPD. 2. Patients in the metoprolol group...

1. In this double-blind randomized trial of COPD patients without previous indication for beta blocker therapy, treatment with extended-release beta-blockers failed to generate improved health outcomes versus placebo. No significant between-group difference was found in the median time until the first exacerbation of COPD. 2. Patients in the metoprolol group...

Beta-blocker medications are commonly used in managing high blood pressure in pregnancy. With an increased prevalence of obesity and related comorbidities in women of reproductive age, exposure to anti-hypertensive medications in early pregnancy has also become more common. The relationship between beta-blocker exposure in utero and the risk of...

1. In this propensity-matched retrospective cohort study, elderly nursing home residents who used beta-blockers after an acute myocardial infarction, especially those with underlying cognitive or functional impairment, were more likely to have a decrease in function compared with those not using beta-blockers. 2. However, use of beta-blockers post-myocardial infarction had...

1. Amongst Danish patients with uncomplicated hypertension, using beta-blockers as part of a two-drug anti-hypertensive regimen led to greater major adverse cardiac events (MACEs) and mortality in the perioperative setting of non-cardiac surgery compared to regimens with renin-angiotensin system (RAS) inhibitors, calcium channel blockers, or thiazide diuretics. 2. However, the...

1. Beta-blocker therapy did not significantly reduce all-cause mortality or time-to-first cardiovascular hospital admission in patients with heart failure and atrial fibrillation, compared to placebo. 2. However, beta-blockers significantly reduced the all-cause mortality and time-to-first cardiovascular hospital admission in patients with heart failure and normal sinus rhythm, compared to...

1. A history of hypertension for 6 or more years was linked with an increased risk of psoriasis in US women.  2. Women with regular β-blocker usage were at higher risk of psoriasis than those who had never used β-blockers.  Evidence Rating Level: 2 (Good)  Study Rundown: Psoriasis is a systemic disease...

1. In a retrospective analysis of patients who had never had a myocardial infarction, preoperative b-blocker use was not associated with any difference in rates of mortality, stroke, ventilation durations, renal failure, or sternal wound infection.  2. Preoperative b-blocker use was associated with higher rates of new-onset atrial fibrillation.  Evidence Rating...

Image: PD 1. Both ß-blockers (-0.92 mmHg, p<0.001) and nitrates (-0.63 mmHg, p=0.011) were associated with a significantly lower intraocular pressure. 2. Statins and aspirin were initially associated with lower intraocular pressure, but were found to be due to concurrent use of ß-blockers. Evidence Rating Level: 2 (Good) Study Rundown: In this study,...