• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Cardiology

No obesity paradox found between BMI, stroke, and death

byGautam GadeyandJames Jiang
June 2, 2014
in Cardiology, Chronic Disease, Neurology
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

1. Contrary to conclusions suggested by several previous studies, the authors found no evidence of the obesity paradox (lower mortality in obese patients) in patients with stroke.

2. Patients with a higher body mass index (BMI) were more likely to have a stroke at a younger age.

Evidence Rating Level: 2 (Good)

Study Rundown: Obesity is rapidly becoming an epidemic in several societies.  While obesity is one of the causes implicated in several chronic diseases, paradoxically several studies seem to also find a pattern of lower mortality in obese patients, as compared to normal or underweight patients, when affected by these chronic conditions.  This phenomenon known as the obesity paradox is not well understood and may be an artificial finding due to selection bias.

This study examined the obesity paradox by analyzing survival rate in patients after stroke in relation to body mass index.  Utilizing data from the Danish Stroke register, the researchers studied only deaths caused by stroke by including only those reported as such on death certificates and only if death occurred within the first month after stroke.  This reduced selection bias.  The study found no relation between BMI and death after having a stroke.  It did, however, find that patients who were obese were more likely to have a stroke at a younger age.  Strengths of the study include the large population size studied and the adjustment for selection bias as detailed above.

Click to read the study, published today in JAMA Neurology

Relevant Reading: Association between obesity and mortality after acute first-ever stroke: the obesity-stroke paradox

RELATED REPORTS

Time restricted eating not more beneficial than daily calorie restriction

Weight loss and lifestyle changes may improve symptoms of obstructive sleep apnea in overweight men

Improved mortality rates for myocardial infarction, stroke, and pulmonary embolism in patients receiving dialysis between 1998 to 2015

In-Depth [retrospective cohort]: The authors of this study used data from the Danish Stroke Register that contains information on all stroke admissions in Denmark.  Patients with transient ischemic attacks and subarachnoid hemorrhages were excluded from the study.  Survival data was obtained through the Danish Central Person Registry.  Only deaths that occurred within the first month after the index stroke were included to reduce selection bias.

76,617 patients were identified from the registry.  The mean age of these patients was 71.8 years.  7878 of these patients had died within the first month, and 5512 of these patients were identified as having died due to stroke.  Adjustments were made for age, sex, stroke severity according to the Scandinavian Stroke Score, stroke subtype, civil status, cardiovascular risk factors, duration of education, and income. After adjustments, the researchers found no difference in mortality risk within the first month after a stroke among normal weight, overweight, and obese patients.  However, underweight patients did appear to have a significantly increased risk of death after a stroke (HR: 1.16; 95% CI, 1.06-1.26).

Image: CC/Wiki

©2012-2014 2minutemedicine.com. All rights reserved. No works may be reproduced without expressed written consent from 2minutemedicine.com. Disclaimer: We present factual information directly from peer reviewed medical journals. No post should be construed as medical advice and is not intended as such by the authors, editors, staff or by 2minutemedicine.com. PLEASE SEE A HEALTHCARE PROVIDER IN YOUR AREA IF YOU SEEK MEDICAL ADVICE OF ANY SORT.

Tags: BMIobesitystroke
Previous Post

2 Minute Medicine Rewind May 26 – June 02, 2014

Next Post

No difference in kidney function with “on” vs “off-pump” coronary bypass graft

RelatedReports

Sleep duration inversely related to childhood type 2 diabetes risk makers
Cardiology

Time restricted eating not more beneficial than daily calorie restriction

May 13, 2022
Admission may not be needed following sleep apnea surgery
Chronic Disease

Weight loss and lifestyle changes may improve symptoms of obstructive sleep apnea in overweight men

April 28, 2022
Fish oil and aspirin did not reduce arteriovenous fistula failure: The FAVOURED trail
Cardiology

Improved mortality rates for myocardial infarction, stroke, and pulmonary embolism in patients receiving dialysis between 1998 to 2015

April 22, 2022
Stroke expansion following intra-arterial therapy may explain worse outcomes
Cardiology

Reduced bleeding risk with asundexian compared to apixaban in patients with atrial fibrillation

April 19, 2022
Next Post
Remote ischemic preconditioning reduced myocardial injury in CABG patients

No difference in kidney function with “on” vs “off-pump” coronary bypass graft

RAS mutation linked with survival in metastatic colorectal cancer

One-time colon cancer screening may be cost-effective in elderly

X-ray after foreign body removal by esophagoscopy is not cost effective

Azithromycin linked with decreased mortality in elderly pneumonia patients

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

Get 2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Wellness Check: Mental Health
  • #VisualAbstract: Addition of elotuzumab to lenalidomide and dexamethasone did not significantly improve survival outcomes in newly diagnosed, transplant-ineligible multiple myeloma
  • #VisualAbstract: Pretreatment with radiotherapy and two cycles of concurrent cisplatin may reduce toxicity in locally advanced nasopharyngeal carcinoma
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.