Tag: stroke

1. Individuals with moderate-to-severe arm impairment after ischemic stroke experienced greater improvements in arm function after vagus nerve stimulation therapy as compared to those without. 2. There were no severe adverse events reported as related to the trial device. Evidence Rating Level: 1 (Excellent) Study Rundown: Loss of motor function is...

1. Guided selection of antiplatelet therapy reduced rates of major adverse cardiovascular event rates compared to standard therapy. 2. Guided selection strategy was beneficial for both escalation and de-escalation of standard therapy, balancing patient-dependent ischemic and bleeding risks.  Evidence Rating Level: 1 (Excellent) Study Rundown: Patients who undergo percutaneous coronary intervention (PCI)...

1. Polypill plus aspirin treatment was shown to decrease the incidence of cardiovascular events compared to placebo in patients without cardiovascular disease. 2. Adverse events such as hypotension and dizziness were shown to be higher in the polypill-only group compared to the placebo group. Evidence Rating Level: 1 (Excellent) Study Rundown: Polypills combining...

1. Women patients with stroke were 10% less likely than male patients to achieve a door-to-computed tomography time (DTCT) within 25 minutes, the recommended time to prevent delayed treatments. 2. Black patients were 12% less likely, and Hispanic patients 7% more likely than white patients to achieve a DTCT within...

1. Risk of recurrent stroke within 90 days of an index event was comparable among patients with non-consensus TIA and classic TIA. 2. Patients with non-consensus TIA were less likely to seek medical attention after the index event. Evidence Rating Level: 2 (Good) Study Rundown: The risk of stroke following a transient...

1. Pulmonary hypertension (PH) was associated with a 15% increase in odds of prolonged hospitalization. 2. PH was associated with a 31% decrease in odds of routine home discharge. 3. There was no association between PH and in-hospital mortality, though males had 31% higher odds of dying in the hospital compared...

1. Patients with lacunar acute ischemic stroke treated with low-dose alteplase had a lower incidence of intracranial hemorrhage compared with those treated with standard-dose, but did not experience any benefit with regards to disability or death. Evidence Rating Level: 1 (Excellent) Study Rundown: Patients presenting with acute ischemic strike (AIS) routinely...

1. Positive fecal immunochemical test (FIT) results were associated with increased incidences of ischemic stroke, myocardial infarction, and all-cause mortality. Evidence Rating Level: 2 (Good) While fecal immunochemical tests (FIT) is a commonly used and effective screening tool for colorectal cancer (CRC), their clinical use in detecting other diseases is poorly...

1. In patients who had a stroke with unknown time of onset and DWI-FLAIR or perfusion mismatch, IV alteplase resulted in better functional outcomes at 90 days compared to placebo or current standard care. 2. The prevalence of severe disability or death was lower with IV alteplase, but was also...

1. Patients who received rivaroxaban had a statistically significantly longer mean time until occurrence of a major clinical event compared to those who received warfarin. 2. The incidence of secondary-outcome events such as transient ischemic attack (TIA), valve thrombosis, and non-CNS embolism were similar between groups. Evidence Rating Level: 1 (Excellent) Study...