Tag: stroke

Accuracy of tau positron emission tomography as a prognostic marker in preclinical and prodromal Alzheimer disease 1. Tau PET predicted cognitive change and effect sizes were greater than amyloid PET and MRI. 2. MRI mediated the association between tau PET and cognition among Alzheimer’s and amyloid-positive MCI groups. Evidence Rating...

1. Depression was associated with elevated risk for ischemic stroke in veterans living with HIV, particularly in those under 60 years of age. 2. Factors that contributed to this association included alcohol use disorders, cocaine use, and antidepressant use. Evidence Rating Level: 3 (Average) Patients with HIV tend to have fewer of...

1. A nationwide Swedish study demonstrated that patients with congenital heart disease are at an increased risk of developing ischemic stroke compared to controls. Evidence Rating Level: 3 (Average) Congenital heart disease (CHD) is the most common major congenital anomaly, and it is associated with an increased risk of complications...

1. Transferred patients with a large vessel occlusion stroke undergoing endovascular thrombectomy may have faster treatment and improved outcomes from a direct to angiography (DTA) approach versus repeated imaging. 2. Optimizing endovascular thrombectomy workflow using a DTA approach when appropriate may be associated with faster and safer reperfusion therapy. Evidence Rating:...

1. Compared to patients only receiving rate-control treatment, those who received rhythm-control treatment within one year of diagnosis of atrial fibrillation had a lower risk of adverse cardiovascular outcomes. 2. This association was not seen if the treatment was initiated over one year after the diagnosis of atrial fibrillation. Evidence Rating...

1. Individuals with moderate-to-severe arm impairment after ischemic stroke experienced greater improvements in arm function after vagus nerve stimulation therapy as compared to those without. 2. There were no severe adverse events reported as related to the trial device. Evidence Rating Level: 1 (Excellent) Study Rundown: Loss of motor function is one of the most...

1. Individuals with moderate-to-severe arm impairment after ischemic stroke experienced greater improvements in arm function after vagus nerve stimulation therapy as compared to those without. 2. There were no severe adverse events reported as related to the trial device. Evidence Rating Level: 1 (Excellent) Study Rundown: Loss of motor function is...

1. Guided selection of antiplatelet therapy reduced rates of major adverse cardiovascular event rates compared to standard therapy. 2. Guided selection strategy was beneficial for both escalation and de-escalation of standard therapy, balancing patient-dependent ischemic and bleeding risks.  Evidence Rating Level: 1 (Excellent) Study Rundown: Patients who undergo percutaneous coronary intervention (PCI)...

1. Polypill plus aspirin treatment was shown to decrease the incidence of cardiovascular events compared to placebo in patients without cardiovascular disease. 2. Adverse events such as hypotension and dizziness were shown to be higher in the polypill-only group compared to the placebo group. Evidence Rating Level: 1 (Excellent) Study Rundown: Polypills combining...

1. Women patients with stroke were 10% less likely than male patients to achieve a door-to-computed tomography time (DTCT) within 25 minutes, the recommended time to prevent delayed treatments. 2. Black patients were 12% less likely, and Hispanic patients 7% more likely than white patients to achieve a DTCT within...