• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Pulmonology

Noninvasive ventilation beneficial in abdominal surgery patients with hypoxemic respiratory failure

byDaniel FisherandMichael Milligan
March 16, 2016
in Pulmonology, Surgery
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

1. Noninvasive ventilation (NIV) was superior to standard oxygen therapy (SOT) in reducing reintubations for patients with hypoxemic respiratory failure after abdominal surgery.

2. NIV also showed decreased the rate of health care-associated infections, especially pneumonia without an increase in serious adverse events

Evidence Rating Level: 1 (Excellent)

Study Rundown: One of the most dangerous complications during the postoperative period is acute respiratory failure, which often requires tracheal intubation and mechanical ventilation. While standard oxygen therapy (SOT), utilizing supplemental oxygen delivered via diffusion, is considered standard care for many postoperative patients, some have suggested that noninvasive ventilation (NIV) may be superior. In this randomized controlled trial, abdominal surgery patients showing signs of hypoxemic respiratory failure were randomly assigned to SOT or NIV groups. NIV resulted in superior outcomes, including reduced reintubations, decreased time under mechanical intubation and ventilator free days, and fewer health care-associated infections, especially for ICU-acquired pneumonias. In addition, there was no difference between the rates of serious adverse effects between the SOT and NIV groups.

This trial strongly suggests that NIV may be beneficial for postoperative patients after abdominal surgery who develop acute respiratory failure, though more investigation is required to generalize these findings to recovery from other surgical procedures. In addition, the study was underpowered and could not resolve if there was a decrease in mortality at 90 days, though the data trended in that direction and were likely to be significant with a larger cohort. Finally, most of the patients in this cohort were male (76%) and over the age of 60 (~62%), limiting the generalizability of these findings to other patient populations.

Click to read the study in JAMA

Relevant Reading: Continuous positive airway pressure for treatment of postoperative hypoxemia

RELATED REPORTS

#VisualAbstract: Early mobilization after ICU mechanical ventilation does not improve survival

Pressure support ventilation does not improve ventilation status as compared to T-piece ventilation

Resuscitation practices in moderate and late preterm infants are highly variable

In-Depth [randomized controlled trial]: A total of 300 patients with acute respiratory failure within 7 days of abdominal surgery were randomized to an NIV or SOT group, with 7 patients being removed from the study due to ineligibility or revoked consent. Patients in the SOT group received up to 15 L/min of oxygen via nasal cannula or face mask, while those in the NIV group received oxygen through a face mask connected to a ventilator with titratable pressure and FiO2 levels. Exclusion criteria included DNR status, contraindications to NIV, sleep apnea, immediate tracheal reintubations, requirement for an emergent surgical procedure, and previous recruitment in another trial. NIV reduced the rate of reintubations by 12.4% (95%CI -23.5% to -1.3%) without significant differences in gas exchange or number of patients requiring reintubations for reoperation. NIV resulted in more ventilator free days (2.2 days, 95%CI 0.1 to 4.6 days) and fewer health care-associated infections (-17.8%, 95%CI -30.2% to -5.4%), especially for ICU-acquired pneumonia (p = 0.003). At 90 days after surgery, the mortality rate for the NIV patients was 14.9% compared to SOT patients at 21.5%, though this difference was not significant (p = 0.15).

Image: PD

©2016 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: positive pressure ventilationventilation
Previous Post

2 Minute Medicine Rewind March 14, 2016

Next Post

Postextubation administration of high-flow oxygen leads to reduced reintubation and respiratory failure

RelatedReports

#VisualAbstract: Early mobilization after ICU mechanical ventilation does not improve survival
StudyGraphics

#VisualAbstract: Early mobilization after ICU mechanical ventilation does not improve survival

December 1, 2022
Postextubation administration of high-flow oxygen leads to reduced reintubation and respiratory failure
Emergency

Pressure support ventilation does not improve ventilation status as compared to T-piece ventilation

November 18, 2022
Increasing C-section room temperature linked to reduced neonatal, maternal hypothermia
Pediatrics

Resuscitation practices in moderate and late preterm infants are highly variable

August 1, 2022
#VisualAbstract: Tocilizumab reduced COVID-19 disease related adverse health outcomes
StudyGraphics

#VisualAbstract: Tocilizumab reduced COVID-19 disease related adverse health outcomes

March 10, 2021
Next Post
Postextubation administration of high-flow oxygen leads to reduced reintubation and respiratory failure

Postextubation administration of high-flow oxygen leads to reduced reintubation and respiratory failure

Increasing C-section room temperature linked to reduced neonatal, maternal hypothermia

Genetic evidence for causal relationships between maternal obesity-related traits and birth weight

Hypertension survey in China demonstrated high prevalence, low rates of control

Hypertension survey in China demonstrated high prevalence, low rates of control

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • SAR-CoV-2 infection during pregnancy may lead to adverse neurodevelopmental outcomes in male offspring
  • Hyperfractionated radiotherapy reduces complication rates compared to standard fractionation for locally advanced nasopharyngeal carcinoma
  • Lebrikizumab effective in treating moderate-to-severe atopic dermatitis
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • The Scan
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

Want more physician-written
medical news?

Join over 10 million yearly readers and numerous companies. For healthcare professionals
and the public.

Subscribe for free today!

Subscription options