• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • Write for us
  • Contact us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • AccountLog-in/out
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Chronic Disease

Screening mammography may result in overdiagnosis of breast cancer

byShayna BejaimalandJames Jiang
July 8, 2015
in Chronic Disease, Oncology, Public Health
Reading Time: 2 mins read
0
Share on FacebookShare on Twitter

1. Screening mammography practices resulted in an increase in breast cancer incidence.

2. Despite an increased incidence of small breast cancers, there was no associated decrease in incidence of larger breast cancers.

Evidence Rating Level: 2 (Good)

Study Rundown: Screening mammography is intended to decrease breast cancer mortality by detecting smaller cancers at earlier, potentially more treatable stages. However, if the diagnosis of larger breast cancers does not concomitantly decrease, screening mammography may actually be leading to the overdiagnosis of smaller tumors that may not become clinically apparent. The possibility of overdiagnosis has not been thoroughly studied. This study examined the association between rates of screening mammography and the incidence and mortality of breast cancer.

In this study, there was a significant increase in breast cancer incidence, but no difference in breast cancer mortality. There was an increase in detection of small breast cancers. However, no complementary decrease in large breast cancer diagnoses was noted, perhaps indicating that screening mammographies may result in overdiagnosis. Strengths of this study include being a large study with over 16 million women as a study population. However, all ecological studies are subjected to ecological fallacy.

Click to read the study, published today in JAMA Internal Medicine

Click to read an invited commentary in JAMA Internal Medicine

RELATED REPORTS

Screening with digital breast tomosynthesis vs mammography associated with significantly lower risk of advanced breast cancer among women with extremely dense breasts at high risk of breast cancer

#VisualAbstract: Adjuvant capecitabine improves long-term survival in early breast cancer

Several factors influence health programs conducted in the African American Church

Relevant Reading: Quantifying and monitoring overdiagnosis in cancer screening: a systematic review of methods

In-Depth [ecological study]: This study used data from the Surveillance, Epidemiology and End Results (SEER) cancer registries from January 1 to December 31, 2000, which reports from 547 counties in the United States. The authors identified women who were diagnosed with breast cancer, as well as the screening mammography practices from each county. Women that were diagnosed with cancer were followed for the next 10 years for outcomes, including mortality. The exposure of interest was the percentage of women in each county who had a mammogram in the past 2 years as of 2000. The outcomes of interest were the incidence of breast cancer, mortality and tumour size.

There was a positive association between the extent of screening mammography and breast cancer incidence (weighted r 0.54; p < 0.001). However there was no association between breast cancer mortality and the degree of screening mammography (weighted r 0.00; p = 0.98). An increase of 10% in the degree of screening resulted in a 16% increase in breast cancer incidence (RR 1.16, 95%CI 1.13-1.19) with no significant difference in breast cancer mortality (RR 1.01, 95%CI 0.96-1.06). When comparing degree of screening and tumour size, there was a strong association with incidence of small breast cancers (≤2 cm) but no accompanying decrease in the incidence of large breast cancers (>2 cm). Specifically, with a 10% increase in the extent of screening, there was a 25% increase in small breast cancer incidence (RR 1.25, 95%CI 1.18-1.32) and a 7% increase in large breast cancer incidence (RR 1.07; 95%CI 1.02-1.12).

Image: PD

©2015 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about licensing here. No article should be construed as medical advice and is not intended as such by the authors or by 2 Minute Medicine, Inc.

Tags: Breast Cancerbreast cancer screening
Previous Post

Cognitive behavioral therapy effective for insomnia with medical or psychiatric comorbidities

Next Post

Cystic fibrosis gene therapy associated with stabilization of lung function

RelatedReports

2 Minute Medicine Rewind March 4, 2019
Chronic Disease

Screening with digital breast tomosynthesis vs mammography associated with significantly lower risk of advanced breast cancer among women with extremely dense breasts at high risk of breast cancer

June 16, 2022
#VisualAbstract: Adjuvant capecitabine improves long-term survival in early breast cancer
StudyGraphics

#VisualAbstract: Adjuvant capecitabine improves long-term survival in early breast cancer

May 18, 2022
Wellness

Several factors influence health programs conducted in the African American Church

May 18, 2022
#VisualAbstract: Aromatase inhibitors significantly reduce recurrence in  premenopausal women with ER+ breast cancer and ovarian suppression
StudyGraphics

#VisualAbstract: Aromatase inhibitors significantly reduce recurrence in premenopausal women with ER+ breast cancer and ovarian suppression

May 3, 2022
Next Post
BRAF V600E mutations linked with increased mortality in thyroid cancer

Cystic fibrosis gene therapy associated with stabilization of lung function

Severe psoriasis linked with poorly controlled blood pressure

Promising phase 2 results for new plaque psoriasis therapy

Dual PDE3/PDE4 inhibitor may be effective treatment for asthma and COPD

COPD patients show substantial variation in lifetime rate of decline

License Our Award-Winning Physician-Written Medical News and Visual Abstracts

2 Minute Medicine is the leading authoritative medical news licensing service, and the only with reports written by practicing doctors.

LICENSE CONTENT

2MM+ Premium Access

No ads & unlimited access to all current reports, over 9000 searchable archived reports, visual abstracts, Weekly Rewinds, and the online edition of The Classics Series™ textbook.

Subscription Options
2 Minute Medicine

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Vitamin and mineral supplementation associated with minimal to no benefit in the primary preventing of cardiovascular disease and cancer – US Preventative Services Task Force
  • RSVpreF vaccine prevents symptomatic respiratory syncytial virus infection
  • Incidence of Kawasaki disease found to be lower during the COVID-19 pandemic in the United States
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • Wellness
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.