Tag: breast cancer screening

Antiplatelet Therapy vs Anticoagulation Therapy in Cervical Artery Dissection: The Cervical Artery Dissection in Stroke Study (CADISS) Randomized Clinical Trial Final Results Cervical artery dissection is a common cause of ischemic stroke in young patients. Whether antiplatelet (AP) therapy or anticoagulation (AC) therapy is more effective at preventing recurrent stroke...

1. In this prospective cohort study, first-degree family history of breast cancer was associated with increased risk of breast cancer in women 65 years and older. 2. In women 65 to 74 years old, the risk was highest in those with fatty breasts whereas in women 75 years and older...

1. In women both with and without personal history of breast cancer (PHBC), screening MRI was associated with higher biopsy rates compared to mammography. 2. Screening MRI was also associated with lower rates of ductal carcinoma in situ (DCIS) and invasive cancer findings when compared to mammography. Evidence Rating Level: 2...

1. In this retrospective cohort, breast cancer screening was not associated with a reduction in advanced tumors. 2. Breast cancer screening was associated with higher rates of overdiagnosis of invasive breast cancer tumors and ductal carcinoma in situ (DCIS). Evidence Rating Level: 2 (Good) Study Rundown: The purpose of effective breast cancer...

1. After advent of mammography, detection rate of large tumors decreases while detection of smaller tumors increases. 2. The decreased rate of large tumor detection was a direct result of increased detection of smaller tumors and not due to a decreased incidence rate. Evidence Rating Level: 2 (Good) ­ Study Rundown: This retrospective...

1. Simulation models indicated that annual screening, compared to biennial screening, for high-risk women with dense breasts resulted in a greater number of breast cancer deaths averted. 2. Triennial breast cancer screening for average-risk women with low breast density reduced screening harms without impacting number of breast cancer deaths averted. Evidence...

1. Detection rate, recall rate, and rate of disagreement between readers was not affected by changing the reading order of mammograms. 2. The number of patients called back for further testing decreased as more mammograms were read in each batch. Evidence Rating Level: 1 (Excellent) Study Rundown: Interpreting mammograms is a notoriously...

1. Screening mammography practices resulted in an increase in breast cancer incidence. 2. Despite an increased incidence of small breast cancers, there was no associated decrease in incidence of larger breast cancers. Evidence Rating Level: 2 (Good) Study Rundown: Screening mammography is intended to decrease breast cancer mortality by detecting smaller cancers...

1. Microsimulation models demonstrated limited health benefits of supplemental ultrasonography for women with dense breasts and substantial increases in cost. Evidence Rating Level: 2 (Good) Study Rundown: Increased breast density is a risk factor for breast cancer, but its integration into screening remains challenging. An increasing number of states are enacting...

1. After implementation of routine screening in older women, the incidence of early stage breast cancer increased, but there was only a minimal absolute decrease in the incidence of advanced stage breast cancer. 2. For each advanced staged tumor that was detected approximately 20 extra, early stage tumors were...