Tag: adverse pregnancy outcomes

1. Dolutegravir-based antiretroviral therapy regimens effectively suppressed maternal viral load during pregnancy, supporting their use to prevent vertical transmission. 2. Dolutegravir, emtricitabine, and tenofovir alafenamide fumarate carried relatively low risk of adverse fetal outcomes. Evidence Rating Level: 1 (Excellent) Study Rundown: Initiation of antiretroviral therapy (ART) for pregnant women infected with HIV-1...

1. No significant increase in spontaneous abortion, preterm birth, major structural defects, or small for gestational age rates were found in women receiving 9vHPV vaccine during pregnancy (within 19 weeks pregnant). 2. No significant differences were found in adverse birth outcomes when comparing vaccinations in women 22 weeks before last...

While obesity has been shown to increase the risk of developing gestational diabetes mellitus (GDM) and preeclampsia (PE) in pregnancy, the association between metabolic syndrome and adverse pregnancy outcomes has not been investigated. In this multicenter prospective cohort study, 5,530 nulliparous women with singleton pregnancies recruited between November 2004...

1. No significant association between serotonergic antidepressant use and autism spectrum disorder risk was found between exposed and unexposed children. Evidence Rating Level: 2 (Good) Study Rundown: Depression is a common complication during pregnancy. While selective serotonin reuptake inhibitors (SSRIs) are used to treat depression during pregnancy, much remains unknown about...

1. This retrospective study found that genetically elevated maternal BMI and blood glucose levels were associated with higher offspring birth weight. 2. Genetically elevated maternal systolic blood pressure was associated with lower birth weight. Evidence Rating Level: 2 (Good) Study Rundown: Women who are obese, overweight, or develop gestational diabetes are more...

1. Women with a history of hypertensive disorders of pregnancy have a small but significant increased risk of developing cardiomyopathy in the peri-partum period 2. This increased risk of cardiomyopathy persisted for more than five years after the most recent pregnancy Evidence Rating Level: 2 (Good)        Study Rundown: It...

1. From a prospective cohort study, adverse pregnancy outcomes in lupus patients were associated with the presence of lupus anticoagulant, antihypertensive use, and a higher Physician’s Global Assessment score. 2. Absent these risk factors, adverse pregnancy outcomes occurred rarely in patients with stable mild or moderate lupus. Evidence Rating Level: 2...

1. Maternal hemoglobin levels were measured at 2 antenatal visits and delivery, while their infants were followed 1 year later and assessed for gross motor (GM) functions. Prevalence of maternal anemia fell from 67% in the first antenatal visit to 38.4% at the time of delivery. 2. GM scores peaked...

1. The use of antidepressants during the first trimester of pregnancy was not significantly associated with higher risk of congenital cardiac abnormalities in this large, population-based cohort study. 2. The use of paroxetine and sertraline during the first trimester were not significantly linked with higher risk of right ventricular outflow...

Image: PD 1. Women with PCOS were more likely to have a preterm delivery. 2. Among women with PCOS, those who exhibited hyperandrogenism were more likely to experience preeclampsia and preterm delivery. Evidence Rating Level: 2 (Good) Study Rundown: This study found that polycystic ovarian syndrome (PCOS) was associated with adverse...