Tag: amyotrophic lateral sclerosis

1. Sodium phenylbutyrate-taurursodiol slowed the functional decline in patients with amyotrophic lateral sclerosis. 2. The mean rate of change for slow vital capacity and plasma phosphorylated axonal neurofilament H subunit were not significantly different between the treatment and control groups. Evidence Rating Level: 1 (Excellent) Study Rundown: Amyotrophic lateral sclerosis (ALS) causes...
1. A 100mg treatment of tofersen was shown to decrease cerebrospinal fluid (CSF) superoxide dismutase 1 (SOD1) concentration in adults with amyotrophic lateral sclerosis (ALS) due to SOD1 mutations. 2. Lumbar puncture-related adverse events were shown to be present in most participants. Evidence Rating Level: 1 (Excellent) Study Rundown: Amyotrophic lateral sclerosis,...
1. Quantitative susceptibility mapping is both a sensitive and specific imaging technique for the degree of iron deposition in the motor cortex, a useful biomarker in the diagnosis of amyotrophic lateral sclerosis and primary lateral sclerosis.   Evidence Rating: 3 (Average) Study Rundown: Amyotrophic lateral sclerosis (ALS) is currently a diagnosis...
1. Increased ingestion of omega-3 polyunsaturated fatty acids from both vegetables and fish may lower the risk of developing amyotrophic lateral sclerosis (ALS). 2. Total ingestion of omega-6 polyunsaturated fatty acids was not associated with any change in risk of developing ALS. Evidence Rating Level: 2 (Good) Study Rundown: Long-chain polyunsaturated fatty...