Tag: antihypertensives

1. Regardless of cardiovascular disease history and baseline blood pressure, a 5 mmHg reduction in systolic blood pressure reduced relative risk of major cardiovascular events by 10%. 2. These findings support considering antihypertensive medications for patients with increased cardiovascular risk, even those who are normotensive at baseline.  Evidence Rating Level: 1...
1. In this randomized clinical trial, patients who received bariatric surgery were nearly 7 times more likely to achieve at least 30% reduction in the total number of hypertensive medications and nearly 20 times more likely to achieve blood pressure control without medications compared to those who did not...
1. In this prospective cohort study, higher 24-hour and nighttime blood pressure measurements were significantly associated with greater risks of death and a composite cardiovascular (CV) outcome. 2. 24-hour and nighttime blood pressure may be considered optimal measurements for estimating CV risk however, there was only a very modest improvement...
1. In this large, retrospective cohort study of veteran’s health administration (VHA) hospitals, males admitted to the hospital for non-cardiac reasons who had an intensification of their antihypertensive regimen before discharge had an increased risk of readmission and serious adverse events. 2. There was no difference in cardiac events or...
1. In this prospective cohort study, higher 24-hour and nighttime blood pressure measurements were significantly associated with greater risks of death and a composite cardiovascular (CV) outcome. 2. 24-hour and nighttime blood pressure may be considered optimal measurements for estimating CV risk however, there was only a very modest improvement...
Hospital volume and outcomes for acute pulmonary embolism: multinational population-based cohort study Patients with pulmonary embolism (PE) can present with a myriad of symptoms, and without prompt recognition and treatment, are at risk of developing life-threatening complications. The authors of this multinational population-based cohort study (n=39,257) aimed to evaluate whether...
1. In this randomized control trial conducted in Japan, intensive blood pressure control (less than 130/80) was associated with reduced risk of first recurrent stroke. 2. While the target blood pressure was 120/80, average blood pressure actually achieved in the intensive group was 127/78 Evidence Rating Level: 1 (Excellent) Study Rundown: Strokes...
The prevalence of hypertension is rapidly increasing in low-income and middle-income countries (LMICs). To effectively target interventions and monitor progress in hypertension care, it is essential to determine country-specific deficiencies in the hypertension care continuum. However, estimates of health system performance in hypertension care from nationally representative studies in...