Tag: autism

Efficacy and safety of landiolol, an ultra-short-acting β1-selective antagonist, for treatment of sepsis-related tachyarrhythmia (J-Land 3S): a multicentre, open-label, randomised controlled trial 1. Patients receiving landiolol were more likely to achieve target heart rates of 60-94 following sepsis-related tachyarrhythmia and had significantly reduced incidence of new onset arrhythmia Evidence Rating: 1...

1. In a case-control study of children in the Military Health System database, congenital heart disease (CHD) and cardiac surgery were associated with higher odds of autism spectrum disorder (AuSD) diagnosis. 2. Odds of AuSD diagnosis were significantly higher in children with atrial septal defect (ASD) and ventral septal defect...

1. Pivotal response treatment (PRT) is an intervention designed to increase motivation to interact by rewarding effort with natural reinforcement. Children with autism spectrum disorder (ASD) randomized to receive 24 weeks of PRT showed improved frequency of functional utterances compared to children randomized to the control group. 2. Parents of...

1. Pivotal response treatment (PRT) is an intervention designed to increase motivation to interact by rewarding effort with natural reinforcement. Children with autism spectrum disorder (ASD) randomized to receive 24 weeks of PRT showed improved frequency of functional utterances compared to children randomized to the control group. 2. Parents of...

1. In a large Danish cohort study, the measles-mumps-rubella (MMR) vaccine was not significantly associated with autism. 2. There was still no increased risk of autism with vaccination in subgroups of children with various risk factors for autism. Evidence Rating Level: 2 (Good) Study Rundown: In 1998, a controversial in the Lancet reported...

1. A case-control study comparing parent-reported sleep problems demonstrated increased odds for sleep problems among children with ASD compared to children in the general population. 2. Children with ASD also had higher mean parent-reported sleep problem scores and increased odds for sleep problems compared to children with other developmental delays/disorders...

Autism spectrum disorder (ASD) has a poorly understood etiology, with some evidence suggesting that environmental contaminants and air pollution may be potential risk factors. In this cohort study, investigators examined data from 132,256 births in Metro Vancouver, British Columbia, Canada, in order to assess whether maternal monthly mean exposures...

1. The prevalence of autism spectrum disorder (ASD) through the National Survey of Children’s Health (NSCH) was estimated to be 2.5% in children 3-17 years of age. Parents of children with ASD were more likely to have higher health care needs and difficulties in accessing health care. 2. Medication was...

1. Maternal prepregnancy obesity without pregestational diabetes mellitus (PGDM) or gestational diabetes mellitus (GDM) was associated with a slightly increased risk of having a child with a neurodevelopmental or psychiatric disorder. 2. Mothers with severe obesity and insulin-dependent, pregestational diabetes had a sixfold increased risk of having a child with...

1. Maternal use of β-2-adrenergic receptor (B2AR) agonist drugs was found to be associated with an increased risk for autism spectrum disorder (ASD) in the child. 2. Although having overlapping confidence intervals, point estimates of the ASD risk from longer exposures to B2AR agonists (≥45 days) tended to be higher...