Tag: autism

1. Treatment with clioquinol (CQ), a small molecule drug that affects zinc regulation, improved social interaction in two mouse models of autism spectrum disorder (ASD). 2. CQ functioned by increasing zinc concentrations in the brain, which in turn restored the compromised neuronal N-methyl-D-aspartate (NMDA) signaling of mice affected with...
In this section, we highlight the key high-impact studies, updates, and analyses published in medicine during the past week. A Randomized, Controlled Trial of an Aerosolized Vaccine against Measles While an effective injected measles vaccine has been available since 1963, world-wide goals to eliminate measles seek to develop low cost, less...
1. In this study of children with older siblings with or without an autism spectrum disorder (ASD), there was no increased risk of development of an autism spectrum disorder following receipt of the measles-mumps-rubella (MMR) vaccine regardless of their older sibling’s ASD status. 2. Among children with older siblings with...
1. Preexisting maternal type II diabetes was not significantly associated with an increased risk of autism spectrum disorders (ASD) in children. 2. Gestational diabetes mellitus (GDM) diagnosed prior to 26 weeks gestation was found to pose a greater risk of ASD compared to GDM diagnosed after 26 weeks.  Evidence...
1. Administration of oxytocin to a monogenic mouse model of autism improved social interactions 2. Oxytocin treatment during the developmental period was sufficient to improve social behavior in fully developed mice. Evidence Rating Level: 3 (Average) Study Rundown: Autism spectrum disorder (ASD) is a complex and heterogeneous disease. To date, hundreds of...
1. Early developmental markers may predict the future diagnosis of an autism spectrum disorder. 2. Video therapy sessions under the guidance of a therapist may improve behavioral outcomes in infants with developmental markers of autism spectrum disorder (ASD). Evidence Rating Level: 2 (Good)     Study Rundown: In most cases, the...
Originally published by Harvard Health. What Is It? Autism is a developmental disorder of the brain. People with autism have problems communicating and interacting socially. They also may have unusual patterns of behavior, interests and activities. Doctors use the term autism spectrum disorder (ASD). This term includes the five kinds of autism. The...
1. Teaching parents an autism spectrum disorder social intervention in the home, rather than in a clinic group led to significantly better scores in social communication, daily living, social skills, and receptive language skills for their child.  Evidence Rating Level: 1 (Excellent)   Study Rundown: Research has shown that early education...
1. Mothers attending either peer-mentored mindfulness or positive psychology group practice had significant improvement in distress, dysfunctional parent-child interactions, anxiety, depression, insomnia, and life satisfaction during treatment; however, mothers in the mindfulness group had greater improvement in anxiety, depression, and insomnia. 2. Mothers of children with autism spectrum disorder showed...
1. Through a randomized trial of autism interventions in low-resourced children, both a Caregiver-Mediated Module (CMM) and Caregiver-Education Module (CEM) intervention significantly increased joint engagement over time between low-resourced children with autism and their caregivers. 2. The CMM group demonstrated a significantly greater rate of improvement in joint engagement than...