Tag: biomarker

1. Serum IL-6 and TNF-α were strong, independent predictors of disease severity and death among those with suspected and confirmed SARS-CoV-2 infection. Evidence Rating Level: 2 (Good) Hyperinflammatory responses, or cytokine storms, are known results of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), serving as a basis for disease severity and...
Association of Intrinsic Brain Architecture With Changes in Attentional and Mood Symptoms During Development 1. Resting-state functional connectivity between several brain regions may serve as a useful biomarker to predict future neuropsychiatric symptoms such as attention deficits, anxiety, and depression in children. Evidence Rating Level: 2 (Good) Neurodevelopment has become an important...
1. Anti-N-methyl-D-aspartate receptor (Anti-NMDAR) encephalitis is an autoimmune disorder, which can result in behavior changes, psychosis, executive dysfunction, seizures, and catatonia. 2. C-X-C motif chemokine 13 (CXCL13) is a substance that attracts B-cells, and was found to be elevated in the majority of patients with anti-NMDAR encephalitis. It may be...
Image: PD 1. Patients with high suppressor of tumorigenicity 2 (ST2) levels at the initiation of graft-vs-host-disease (GVHD) therapy were more likely to have treatment-resistant GVHD and to die within 6 months of therapy initiation.  2. Plasma ST2 values measured at day 14 after transplantation is a better predictor of death...