Tag: bleeding

1. There was no significant difference in periprocedural myonecrosis between ticagrelor and clopidogrel among patients undergoing high-risk elective PCI. 2. Ticagrelor treatment was associated with an increased rate of minor bleeding at 30 days post-operation. Evidence Rating Level: 1 (Excellent) Study Rundown: Percutaneous coronary intervention (PCI) provides a safe therapeutic option for patients with...
1. Gastrointestinal, genitourinary, or bronchopulmonary bleeding in anticoagulated patients with atrial fibrillation have been associated with higher rates of respective cancer diagnoses. Evidence Rating Level: 2 (Good) Recent registry data suggests that diagnoses of atrial fibrillation (AF) have been associated with higher incidence rates of cancer. Bleeding episodes in anticoagulated patients...
1. Low dose edoxaban was superior to placebo in preventing stroke or systemic embolism for very elderly patients with nonvalvular atrial fibrillation at risk of bleeding. 2. Edoxaban did not significantly increase the incidence of major bleeding compared to placebo. Evidence Rating Level: 1 (Excellent) Study Rundown: Atrial fibrillation and age are...
1. Bleeding after percutaneous coronary intervention (PCI) was more common in women, but the effect of two antiplatelet strategies on death and new Q-wave myocardial infarction following PCI did not differ between men and women. Evidence Rating Level: 1 (Excellent) Percutaneous coronary intervention (PCI) is a highly effective treatment in coronary...
Bleeding after percutaneous coronary intervention (PCI) was more common in women, but the effect of two antiplatelet strategies on death and new Q-wave myocardial infarction following PCI did not differ between men and women. Evidence Rating Level: 1 (Excellent) Percutaneous coronary intervention (PCI) is a highly effective treatment in coronary...
1. The Perioperative Anticoagulation Use for Surgery Evaluation (PAUSE) cohort study evaluated the safety of standardized perioperative interruption of direct oral anticoagulants (DOACs) for patients with atrial fibrillation undergoing operative interventions. The rates of both major bleeding and arterial thrombosis were low during the study period. 2. Most patients had...
1. Based on a retrospective cohort study of US Medicare patients, rivaroxaban was associated with a significantly increased risk of intracranial and extracranial hemorrhage compared with dabigatran when used in elderly patients with nonvalvular atrial fibrillation for stroke prevention. 2. There was a trend towards a decrease in thromboembolic stroke...
1. Based on a matched control study of elderly patients for whom anticoagulation was indicated, bleeding risk was mildly higher in patients 90 or older and the same amongst patients 80-89 years old as compared with those between ages 70-79 years old. 2. The risk of thrombosis was significantly higher...
1. In patients who underwent percutaneous biopsy, clinically significant post-procedural hemorrhage is very uncommon, occurring in roughly three per thousand procedures. Delayed pain was the most common compliant following these diagnostic procedures. 2. Percutaneous biopsies of patients on anticoagulant therapy or of native kidneys posed the greatest risk of post-procedural...