Tag: cardiovascular mortality

1. Sleep duration, when adjusted for body mass index (BMI), had an association with all-cause mortality at lower and higher durations. 2. Short and long sleep duration was associated with increased cardiovascular mortality risk and other-case mortality in men. Long sleep duration was also associated with an increased cancer mortality...

1. Time spent cycling was associated with lower all-cause and cardiovascular disease-specific mortality in this multicenter European cohort study of patients with diabetes, independent of other exercise. 2. Taking up cycling over a five-year period was associated with lower mortality rates compared with those who did not cycle at all. Evidence...

1. Weight loss surgery was associated with significant improvement in both macrovascular and microvascular function across subgroups of sex, race, and metabolic syndrome in addition to effective weight loss. 2. Variation in vascular response to bariatric intervention across subgroups underscores heterogeneity in physiological responses to weight loss and potential activation...

1. Clopidogrel monotherapy reduced long-term rates of all-cause mortality, non-fatal myocardial infarction, and stroke after drug-eluting stent placement compared with aspirin monotherapy. 2. The superiority of clopidogrel was seen for both thrombotic and bleeding endpoints and was consistent across demographic groups. Evidence Rating Level: 1 (Excellent)  Study Rundown: Patients who receive percutaneous...

1. Regardless of cardiovascular disease history and baseline blood pressure, a 5 mmHg reduction in systolic blood pressure reduced relative risk of major cardiovascular events by 10%. 2. These findings support considering antihypertensive medications for patients with increased cardiovascular risk, even those who are normotensive at baseline.  Evidence Rating Level: 1...

1. Patients without standard modifiable cardiovascular risk factors (SMuRFs) had a significantly higher all-cause mortality at 30 days after first presentation of STEMI. 2. Patients without SMuRFs were significantly less likely to receive statins, ACEIs, ARBs, or beta-blockers at discharge.  Evidence Rating Level: 2 (Good) Study Rundown: Standard modifiable cardiovascular risk factors...

1. Positive fecal immunochemical test (FIT) results were associated with increased incidences of ischemic stroke, myocardial infarction, and all-cause mortality. Evidence Rating Level: 2 (Good) While fecal immunochemical tests (FIT) is a commonly used and effective screening tool for colorectal cancer (CRC), their clinical use in detecting other diseases is poorly known....

1. Patients who received low-dose colchicine daily had a ~30% lower risk of cardiovascular events compared to those who received placebo. 2. Although the incidence of cardiovascular death was similar between groups, the colchicine group had a numerically greater number of non-cardiovascular deaths as well as all-cause deaths compared to...

1. Compared to healthy matched controls, individuals with multiple sclerosis demonstrated significantly increased risk of cerebrovascular disease, acute coronary syndrome, cardiovascular disease-related mortality, and all-cause mortality. Evidence Rating Level: 2 (Good) Multiple sclerosis (MS) is an autoimmune disease characterized by the demyelination of nerve fibers in the central nervous system, resulting in...

Association of Use of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers With Testing Positive for Coronavirus Disease 2019 (COVID-19) 1. No association was found between angiotensin-converting enzyme inhibitor or angiotensin II receptor blocker use and test-positivity for COVID-19. Evidence Rating Level: 2 (Good) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the...