Tag: cardiovascular

1. The standardized Ready to Reduce Risk (3R) program resulted in improvements to lifestyle among those taking medication for prevention of cardiovascular disease. 2. 3R did not improve medication adherence compared to the control group. Evidence Rating Level: 2 (Good) Nearly one-third of deaths across the globe are attributable to cardiovascular disease...
1. Patients status-post placement of drug-eluting stents (DES) for acute coronary syndrome received three months of Ticagrelor and Aspirin dual-antiplatelet therapy (DAPT), followed by nine months of DAPT or Ticagrelor monotherapy. 2. At one year, patients who received Ticagrelor alone experienced significantly fewer adverse major bleeding events. There was no...
1. Gut Bacterial Species Shown to Lower Fecal and Serum Cholesterol Levels in Humans Evidence Rating Level: 2 (Good) High serum cholesterol levels have been linked to cardiovascular disease, the cause of 1 in 4 deaths in all industrialized countries. Reducing cholesterol transport in the intestine, as demonstrated by ezetimibe, a...
1. Among 2.3 million individuals (42.3 million patient years of follow-up), in those who had a BMI in the mid-normal range (50th to 74th percentile) at seventeen years of age, the rate of fatal cardiovascular events in adulthood demonstrated a significant increase compared to the 5th to 24th percentiles...
1. Based on interim analysis after 25% and 50% of expected events, among obese patients naltrexone-bupropion treatment resulted in lower risk of first major adverse cardiovascular event and cardiovascular death. 2. The most common events leading to discontinuation of therapy included GI and CNS symptoms, which occurred more often in...
Image: PD  1. In a large cohort study, fertility therapy was not associated with increased risk of maternal cardiovascular events.  2. Fertility therapy was associated with an increased risk of maternal metabolic syndromes during pregnancy, including gestational diabetes, pre-eclampsia and eclampsia.  Evidence Rating Level: 2 (Good)             Study Rundown:...
Image: PD 1. In a retrospective study, preterm delivery was an independent risk factor for future maternal cardiovascular-related hospitalizations.  2. The risk of maternal cardiovascular morbidity increased in a dose-dependent fashion with the number of preterm births.  Evidence Rating Level: 2 (Good)  Study Rundown: This population-based, retrospective cohort study identified a dose-dependent increase...
Image: PD 1. Intensive lifestyle intervention in overweight and obese patients with type II diabetes reduced weight, hemoglobin A1c levels, and improved many risk factors for cardiovascular disease.  2. Intensive lifestyle intervention in overweight and obese patient did not significantly affect a cardiovascular events.   Evidence Rating Level: 1 (Excellent)  Study Rundown: This is the...
Image: PD 1. Weight gain between 0 and 18 months of age is independently associated with childhood excess weight and poor cardiovascular health markers.  2. Breastfeeding for at least the first 6 months of life was associated with lesser weight gain.  Evidence Rating Level: 2 (Good)  Study Rundown: Researchers investigated the potential effect...