Reducing saturated fat decreases mortality in high-risk individuals
1. In this systematic review, reducing intake of saturated fatty acids (SFAs) showed possible benefit for mortality, non-fatal myocardial infarction ...
Tag: cholesterol
Novel inhibitory antibody, MAR001, lowers triglycerides and remnant cholesterol in humans
1. ANGPTL4 inhibition decreased triglyceride and remnant cholesterol levels by over 50%. 2. MAR001 was well-tolerated with no significant treatment-related ...
Obicetrapib and ezetimibe combination therapy lowers LDL cholesterol in high-risk patients
1. FDC obicetrapib plus ezetimibe significantly decreased LDL cholesterol levels by 48.6% compared to placebo. 2. Serious adverse events were ...
Mirum: Ctexli reduces cholesterol metabolite build-up in patients with cerebrotendinous xanthomatosis
Ctexli significantly reduced levels of two atypical cholesterol metabolites usually elevated in patients with cerebrotendinous xanthomatosis (CTX) compared to the ...
Time-restricted eating may improve glycemic control in patients with metabolic syndrome
1. In this randomized controlled trial, patients with metabolic syndrome who underwent time-restricted eating in addition to standard-of-care counseling had ...
Avocado consumption was associated with lower cardiometabolic risk measures
1. Participants who identified themselves as avocado consumers had lower body mass index, waist circumference, plasma glucose, and cholesterol level ...
Urgent need for improved detection of pediatric familial hypercholesterolemia worldwide
1. 92.4% of children in high-income countries had heterozygous familial hypercholesterolemia compared to 48.0% in non-high-income countries. 2. The majority ...
Vascular Function Improvements Derived From Exercise Are Not Sex-Dependent
1. The exercise training prevented increases in total cholesterol and LDL cholesterol which were observed in the non-exercise group and ...
C-reactive protein may have superior prognostic value compared to low-density lipoprotein cholesterol for patients on statin therapy
1. High-sensitivity C-reactive protein increased the risk of all-cause mortality by two- to three-fold among all three randomized trials. 2. ...
![Ivabradine ineffective in stable coronary artery disease [SIGNIFY trial]](https://www.2minutemedicine.com/wp-content/uploads/2014/09/800px-RCA_atherosclerosis-350x250.jpg)
Olpasiran significantly reduces lipoprotein(a) levels in patients with cardiovascular disease
1. Olpasiran significantly and substantially reduced lipoprotein(a) concentration in patients with atherosclerotic cardiovascular disease compared to placebo. 2. Olpasiran reduced ...
