Resistance Exercise Therapy After COVID-19 Infection: A Randomized Clinical Trial
1. Resistance exercise for three months improved physical function and psychological well-being among adults after COVID-19 infection. Evidence Rating Level: ...
Tag: clinical trial
Menin inhibition with revumenib for NPM1-mutated relapsed or refractory acute myeloid leukemia: the AUGMENT-101 study
1. In pretreated patients with nucleophosmin 1-mutated (NPM1m) acute myeloid leukemia (AML), nearly half of patients treated with revumenib showed ...
mFOLFIRINOX may have a limited role in pancreatic cancer in Phase II/III trial
1. In patients with metastatic pancreatic cancer, neither modified fluorouracil, leucovorin, irinotecan and oxaliplatin (mFOLFIRINOX) or S-1, irinotecan and oxaliplatin ...
Artificial Intelligence and Real World Data Speed Up Drug Development
Key points:1. TriNetX is using real world data to reduce clinical trial enrollment time by as much as 40 percent2. ...
![2MM: AI Roundup- AI Cancer Test, Smarter Hospitals, Faster Drug Discovery, and Mental Health Tech [May 2nd, 2025]](https://www.2minutemedicine.com/wp-content/uploads/2025/05/Untitled-design-350x250.png)
2MM: AI Roundup – FDA’s AI Push, Trial Speedups with Real-World Data, Smart Surgical Monitors, and Regulatory Overhaul Begins [May 23rd, 2025]
Food and Drug Administration to Fully Integrate Generative Artificial Intelligence by JuneThe Food and Drug Administration is diving headfirst into ...
RAMOSE Phase II trial finds promising results for osimertinib and ramucirumab in non-small cell lung cancer
1. Treatment of patients with tyrosine kinase inhibitor (TKI)-naïve epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC) with ...
Dose-dense adjuvant therapy with epirubicin and cyclophosphamide effective for breast cancer
1. Dose-dense adjuvant chemotherapy involving sequential epirubicin/cyclophosphamide and docetaxel showed improved breast cancer recurrence-free survival and event-free survival compared to ...
Phase I trial of novel CAR-T cell therapy for pediatric midline gliomas
1. Approximately 88% of patients with GD2-positive diffuse midline glioma or other progressive CNS tumours receiving C7R-GD2.CARTs had a partial ...
A large language model demonstrates superior cost-effectiveness in screening heart failure candidates for clinical trials
1. Unlu and colleagues compared RECTIFIER, a large language model (LLM), against human study staff to evaluate patient eligibility for ...
Mustang Bio & City of Hope: CAR-T Cell Therapy Extends Treatment Refractory Glioblastoma Survival
Half the individuals receiving the new CAR-T cell therapy achieved stable disease or better. Intratumoral, intraventricular, and intratumoral + intraventricular ...
