Tag: cognitive development

1. Rates of severe and moderate neurodevelopmental disabilities increased as gestational age group decreased. 2. Approximately half of children born between 24-26 weeks’ gestation needed at least one developmental intervention, versus a quarter of children born at 32-34 weeks.  Evidence Rating Level: 2 (Good) Study Rundown: Approximately 10% of babies in North...
1. Height-for-age z-score was negatively associated with brain functional connectivity (FC), with FC serving as a mediating factor between child growth and future intellectual functioning in a sample of impoverished children. Evidence Rating Level: 2 (Good) Poverty and early childhood adversity are known risk factors for neurodevelopmental delays and chronic disorders....
1. Patients born both extremely premature and with severe growth restriction were found to have decreased level of functioning in multiple cognitive domains when assessed at 10 years old. 2. In addition to cognitive delays, patients born extremely premature with severe growth restriction were found to have a myriad of...
1. Executive function (EF) performance remained stable from 8 to 18 years old among the majority of children born extremely premature (EP) or with extremely low birth weight (ELBW). 2. EP and ELBW children with typical EF development outperformed children with persistent, intermittent, or late-onset deficits in all academic domains. Evidence...
1. Among extremely preterm infants, low-dose hydrocortisone was not associated with adverse neurodevelopmental outcomes at 2 years of age. Evidence Rating Level: 1 (Excellent) Study Rundown: Close to 15 million preterm neonates are born every year and many of these children suffer from significant complications. Glucocorticoids have been utilized as a...
1. In this prospective cohort study, New Zealand children with increased lead levels in their blood had significantly lower cognitive skills and socioeconomic status in adulthood compared to children with lower lead levels. 2. The link between childhood lead levels and lower adulthood socioeconomic status was primarily mediated through cognitive...
1. In children entering kindergarten, the lowest and highest socioeconomic quintiles had a difference of 33 and 37 percentile points in reading and math scores, respectively. 2. Differences in family background, health factors, home learning environment, parenting style/beliefs, and early education accounted for over half of the gap noted above.  Evidence Rating Level:...
Very preterm (VPT) infants with small biparietal width (BPW) and increased interhemispheric distance (IHD), measurements of brain growth at term (37-42 weeks gestation) by magnetic resonance imaging (MRI), were both independently associated with impaired cognitive development at age 2. Evidence Rating Level: 2 (Good)   Study Rundown: MRI aids in the...
Classics Series, Landmark Trials in Medicine
Image: PD 1. Among children exposed to lead early in life, serum lead levels at 24 months of age were significantly associated with decreased cognitive performance on measures of intelligence and educational achievement at 10 years old. 2. Each 0.48 μmol/L (10 μg/dL) increase in serum lead at 24 months of...
Image: PD 1. Women with mild-to-moderate iodine deficiency in their first trimester of pregnancy were more likely to have children in the lowest quartile of verbal and reading IQ tests at ages 8 and 9.  2. The average woman studied was mild-to-moderately iodine deficient such that even in industrialized nations, iodine...