• About
  • Masthead
  • License Content
  • Advertise
  • Submit Press Release
  • RSS/Email List
  • 2MM Podcast
  • Write for us
  • Contact Us
2 Minute Medicine
No Result
View All Result

No products in the cart.

SUBSCRIBE
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
2 Minute Medicine
  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan+
  • Classics™+
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
SUBSCRIBE
2 Minute Medicine
Subscribe
Home All Specialties Pediatrics

Impaired brain growth in preterm infants linked with delayed cognitive development

byBrandon ChildsandWilliam Raszka, MD
July 28, 2014
in Pediatrics
Reading Time: 3 mins read
0
Share on FacebookShare on Twitter

Very preterm (VPT) infants with small biparietal width (BPW) and increased interhemispheric distance (IHD), measurements of brain growth at term (37-42 weeks gestation) by magnetic resonance imaging (MRI), were both independently associated with impaired cognitive development at age 2.

Evidence Rating Level: 2 (Good)  

Study Rundown: MRI aids in the identification of brain injuries in preterm infants. However, imaging results may not always correlate with future neurodevelopmental impairments, such as cognitive and behavioral challenges. The purpose of this study was to further understand (using MRI measurements) how brain injury and brain growth in VPT infants are related to developmental outcomes at 2 years of age. Researchers found that infants with higher grade brain injuries had delayed neurodevelopmental function at 2 years. Similarly, the lowest cognitive function at age 2 was seen in preterm infants with both small BPW and increased IHD on MRI scan at term. Results may be limited as the gold standard for brain volume measurement was not used, cohorts were located in different regional environments and received different treatments. These findings may aid physicians in their predictions for future neurodevelopment of preterm infants with these specific brain growth measurements.

Click to read the study, published today in Pediatrics

Relevant Reading: Neurobehavioral outcomes of school-age children born extremely low birth weight or very preterm in the 1990s

In-Depth [prospective cohort study]: Data obtained from the charts of 325 infants from 3 different cohorts (Christchurch Women’s Hospital in Christchurch, New Zealand; Royal Women’ Hospital in Melbourne, Australia; St. Louis Children’s Hospital in St. Louis, Missouri) born at <30 weeks gestation and with an MRI obtained at ≥37 and ≤42 weeks gestation were examined. Neurodevelopment was assessed in children at age 2 using the Bayley Scales of Infant Development. Brain injuries (Pariventricular leukomalacia-PVL, cerebellar hemorrhage-CBH, and intraventricular hemorrhage-IVH) were seen in 33% of all participants and high grade injuries were identified in 10%. In the Christchurch and Melbourne cohorts, children with high grade PVL (P <.001) or IVH (P <.05) had the lowest neurodevelopmental scores at age 2 compared to those without any brain injury. A similar trend was observed in the St. Louis cohort. Multivariable analysis demonstrated that small BPW (P = 001) and increased IHD (P < .001) were independently associated with decreased cognitive ability at 2 years of age.

RELATED REPORTS

Impaired lipoprotein cholesterol ratio is associated with cognitive impairment in patients with stroke

Risk factors associated with cognitive impairment development in older adults

Early antibiotics in noncritical premature infants without clear infection linked to adverse outcomes

More from this author: Delayed umbilical cord clamping associated with potential antioxidant effect, Standardized patient handoff process associated with decrease in handoff errors, Youth exposure to e-cigarette advertisements increasing, Decreased sleep in childhood linked with later central adiposity, Food advergames linked to increased caloric intake in children

Image: PD

©2012-2014 2minutemedicine.com. All rights reserved. No works may be reproduced without expressed written consent from 2minutemedicine.com. Disclaimer: We present factual information directly from peer reviewed medical journals. No post should be construed as medical advice and is not intended as such by the authors, editors, staff or by 2minutemedicine.com. PLEASE SEE A HEALTHCARE PROVIDER IN YOUR AREA IF YOU SEEK MEDICAL ADVICE OF ANY SORT.  

 

 

Tags: cognitive developmentcognitive impairmentpremature infant
Previous Post

Protocol-driven Neonatal Abstinence Syndrome care effective

Next Post

Novel pill-only regimens effective against hepatitis C [COSMOS and HALLMARK-DUAL study]

RelatedReports

Quick Take: Functional Outcome of Intravenous Thrombolysis in Patients With Lacunar Infarcts in the WAKE-UP Trial
Chronic Disease

Impaired lipoprotein cholesterol ratio is associated with cognitive impairment in patients with stroke

June 4, 2025
Chronic Disease

Risk factors associated with cognitive impairment development in older adults

January 18, 2024
Quick Take: Analgesic efficacy and safety of morphine in the Procedural Pain in Premature Infants (Poppi) study: randomised placebo-controlled trial
Chronic Disease

Early antibiotics in noncritical premature infants without clear infection linked to adverse outcomes

April 25, 2023
Large proportion of late preterm infants and older admitted to the NICU
Obstetrics

Neonatal docosahexaenoic acid supplementation is associated with higher IQ scores at five years of age

October 31, 2022
Next Post
Study lends support for interferon-free treatment of hepatitis C

Novel pill-only regimens effective against hepatitis C [COSMOS and HALLMARK-DUAL study]

Pro-vaccine messages not associated with increased vaccination intent

AAP updates meningococcal vaccine recommendations

Malarial transmission substantially reduced in endemic Africa

2 Minute Medicine Rewind July 20 – July 27, 2014

2 Minute Medicine® is an award winning, physician-run, expert medical media company. Our content is curated, written and edited by practicing health professionals who have clinical and scientific expertise in their field of reporting. Our editorial management team is comprised of highly-trained MD physicians. Join numerous brands, companies, and hospitals who trust our licensed content.

Recent Reports

  • Artificial intelligence may assist in early detection of decreased ejection fraction on echocardiograms
  • #VisualAbstract: Tarlatamab Improves Survival in Small-Cell Lung Cancer after Platinum-Based Chemotherapy
  • Large language models show potential to provide feedback on research papers on a large-scale
License Content
Terms of Use | Disclaimer
Cookie Policy
Privacy Statement (EU)
Disclaimer

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.

  • Specialties
    • All Specialties, All Recent Reports
    • Cardiology
    • Chronic Disease
    • Dermatology
    • Emergency
    • Endocrinology
    • Gastroenterology
    • Imaging and Intervention
    • Infectious Disease
    • Nephrology
    • Neurology
    • Obstetrics
    • Oncology
    • Ophthalmology
    • Pediatrics
    • Pharma
    • Preclinical
    • Psychiatry
    • Public Health
    • Pulmonology
    • Rheumatology
    • Surgery
  • AI Roundup
  • Pharma
  • The Scan
  • Classics™
    • 2MM+ Online Access
    • Paperback and Ebook
  • Rewinds
  • Visual
  • Podcasts
  • Partners
    • License Content
    • Submit Press Release
    • Advertise with Us
  • Account
    • Subscribe
    • Sign-in
    • My account
No Result
View All Result

© 2021 2 Minute Medicine, Inc. - Physician-written medical news.