Tag: premature infant

1. In this retrospective cohort study reviewing data from 2006 to 2017, researchers showed very premature infants identified as African American had more rapid declines in infant mortality, hypothermia, necrotizing enterocolitis (NEC),and length of stay as compared to white infants, while infants identified as Hispanic had more rapid declines...
Infant pain is often undertreated, largely due to a lack of evidence surrounding the immediate and long-term effects of analgesics. In this randomized controlled trial, 31 infants were randomized to receive either 100 μg/kg oral morphine sulphate or placebo 1 hour before a clinically required heel lance and retinopathy...
1. Infants born to mothers who used medications for treatment of attention-deficit/hyperactivity disorder (ADHD) during pregnancy had increased risk of central nervous system (CNS) disorders, prematurity, and admission to the neonatal intensive care unit (NICU). 2. ADHD medication use during pregnancy was not associated with increased risk of neonatal mortality...
1. In this population-based cohort study, any antenatal corticosteroid (ANS) administration was associated with lower infant mortality than no ANS. The largest risk reduction was seen with ANS administered 24 hours to 7 days before delivery. 2. Simulation model analyses of infants who had not received ANS predicted decreases in...
1. In an underpowered study, infants less than 28 weeks were more than 3 times more likely to die if given room air during resuscitation. 2. Overall, infants less than 32 weeks’ gestational age resuscitated with room air versus 100% oxygen did not have significant differences in morbidity or mortality Evidence...
1. Greater airway obstruction in adolescence was observed in both females and males who were born moderate-to-late preterm compared to term controls. 2. No evidence of catch-up in lung function was observed between 8 and 16 years of age. Evidence Rating Level: 2 (Good) Study Rundown: Lung development in preterm infants (<37...
1. From 2000 to 2011, the overall mortality of extremely premature infants decreased. 2. Death attributed to pulmonary and infectious causes decreased, while deaths attributed to necrotizing enterocolitis increased. Evidence Rating Level: 1 (Excellent) Study Rundown: Prematurity continues to be one of the leading causes of neonatal mortality. Extremely premature...
1. When compared to iron-folic acid supplementation, maternal multiple micronutrient supplementation demonstrated no difference in 6 month infant mortality in a cluster randomized trial performed in rural Bangladesh. 2. In contrast, maternal multiple micronutrient supplementation was associated with a statistically significant decrease in the number of pre-term and low weight...
Very preterm (VPT) infants with small biparietal width (BPW) and increased interhemispheric distance (IHD), measurements of brain growth at term (37-42 weeks gestation) by magnetic resonance imaging (MRI), were both independently associated with impaired cognitive development at age 2. Evidence Rating Level: 2 (Good)   Study Rundown: MRI aids in the...
Image: PD  1. Non-invasive continuous positive airway pressure (CPAP) reduced rates of death or bronchopulmonary dysplasia compared with intubation in preterm infants.  2. CPAP was associated with lower rates of surfactant use and mechanical ventilation.  Evidence Rating Level: 1 (Excellent)        Study Rundown: This systematic review and meta-analysis found that non-invasive...