Tag: diabetes mellitus

1. In patients with type 2 diabetes and an estimated glomerular filtration (eGFR) rate of ≥ 30 mL per minute per 1.73 m2 of body-surface area that received empagliflozin, there was reduced incidence of new or worsening nephropathy, less incidence of doubling of creatinine and less initiation of renal-replacement...
1. There was no difference in cardiovascular or all-cause mortality between any of the various glucose-lowering agent combinations 2. Each drug combination had a different profile with regards to body weight, risk of hypoglycemia, and risk of treatment failure, indicating that diabetic regimens should be personalized. Evidence Rating Level: 1 (Excellent) Study...
1. Based on retrospective data analysis of a national cohort, although clinically complex type 2 diabetics were more likely to be managed with lifestyle changes or a single oral agent, about 20% still received intensive diabetes treatment, going against standard recommendations. 2. Patients with high clinical complexity who received intensive...
1. Neighborhoods with the highest degree of walkability had the lowest rates of obesity and diabetes. 2. Rates of walking, cycling, and public transit use were significantly higher and car use was lowest in the most walkable neighborhoods. Evidence Rating Level: 2 (Good) Study Rundown: It is well known that rates of...
1. In this systematic review and meta-analysis, the use of weekly glucagon-like peptide-1 receptor agonists (GLP1-RAs) was associated with a significant reduction in fasting glucose and HbA1c when compared to placebo. 2. Of the weekly GLP1-RAs compared, duraglutide, exenatide and taspoglutide were associated with the greatest decrease in fasting glucose...
1. Based on Veterans Affairs primary care data on older adults with longstanding diabetes, deintensification of hypertension therapy, not including angiotensin converting enzyme inhibitors (ACE-I) amongst patients with moderately low and very low blood pressures (BP) occurred less than 20% of the time. 2. Similarly, deintensification of diabetes therapy, not...
1. From a systematic review, behavioral programs offering more than 11 contact hours led to clinically important improvements in patients with type 2 diabetes. 2. While lifestyle and diabetes self-management programs had equal effects on glycemic control, lifestyle programs had greater impact on BMI. 3. Programs tended to benefit those with...
1. From a systematic review, diet and physical activity promotion programs were linked to decreased risk factors for diabetes, as well as incidence of new cases. 2. More intense programming was associated with better outcomes. Evidence Rating Level: 1 (Excellent) Study Rundown: An estimated 1.7 million new cases of diabetes are diagnosed...
1. In patients with suspected pancreatic disease, diffusion kurtosis imaging of the pancreas may be used to predict hemoglobin A1c values. 2. Following pancreatic diffusion kurtosis infusion, mean kurtosis values were positively correlated with HbA1c values, suggesting MK measurement may be a potential marker of HbA1c levels or the histopathological...