Tirzepatide improves blood sugar control in metformin-refractory type 2 diabetes
1. In this randomized controlled trial, tirzepatide produced substantially greater reductions in HbA1c, body weight, waist circumference, and BMI than ...
Tag: diabetes mellitus
Dipeptidyl peptidase-4 inhibitors may be associated with an increased incidence of malignancy
1. Sitagliptin demonstrated the most prominent malignancy-related safety signal among the dipeptidyl peptidase-4 inhibitors studied. Evidence Rating Level: 2 (Good) ...
C-peptide levels during oral glucose tolerance test may be a useful biomarker for early detection of gestational diabetes mellitus
1. 30- and 60-minute C-peptide levels during an oral glucose tolerance test (OGTT) at 16–18 weeks gestation were significantly elevated ...
Energy-reduced Mediterranean diet with increased physical activity may significantly reduce risk of type 2 diabetes
1. In this secondary analysis of a randomized controlled trial, physical activity paired with an ad libitum energy-reduced Mediterranean diet ...
Glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors associated with similar dementia risk in older adults
1. In this target trial emulation, glucagon-like peptide-1 receptor agonists (GLP-1 RAs) did not significantly affect the risk of dementia ...
“Weekend warrior” and regular physical activity patterns may both reduce cardiovascular and all-cause mortality
1. In this prospective cohort study of adults with diabetes, “weekend warrior” and regular physical activity patterns were associated with ...
#VisualAbstract: Cagrilintide-Semaglutide is Effective for Weight Loss in Adults with Overweight or Obesity and Type 2 Diabetes
Click here to read this study in NEJM. ©2025 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced ...
Tirzepatide-associated improvements in cardiometabolic risk factors linked to degree of weight loss
1. In this post-hoc analysis of the SURMOUNT-1 trial, there was a mostly linear relationship between percentage change in weight ...
Semaglutide improves walking ability in patients with peripheral artery disease and type 2 diabetes
1. Maximum walking distance at 52 weeks was significantly improved with semaglutide. 2. There were fewer treatment-related serious adverse events ...
Glucagon-like Peptide-1 Receptor Agonists and Lower Depression Risk in Older Adults with Diabetes
Click here to read the study in Annals of Internal Medicine ©2025 2 Minute Medicine, Inc. All rights ...
