Tag: Eczema

1. In this study, nemolizumab with topical agents and oral antihistamines when compared to topical agents and oral antihistamines alone reduced pruritis in atopic dermatitis patients 2. Among patients in the nemolizumab group, eczema area, quality of life and insomnia improved when compared with placebo. Evidence Rating Level: 1 (Excellent) Study Rundown:...

1. In treatment-resistant childhood atopic dermatitis, omalizumab significantly reduced the severity of dermatitis and improved quality of life compared to placebo.  Evidence Rating Level: 1 (Excellent) Anti-IgE medications such as omalizumab are well-tolerated in patients with severe asthma and atopy; however, no large randomized trials have examined its efficacy in children experiencing...

1. In treatment-resistant childhood atopic dermatitis, omalizumab significantly reduced the severity of dermatitis and improved quality of life compared to placebo.  Evidence Rating Level: 1 (Excellent) Anti-IgE medications such as omalizumab are well-tolerated in patients with severe asthma and atopy; however, no large randomized trials have examined its efficacy in children...

PD-1 blockade in advanced adrenocortical carcinoma 1. Pembrolizumab may provide clinically meaningful anti-tumor activity in the setting of adrenocortical carcinoma, particularly in tumors characterized by microsatellite instability and/or mismatch repair  Evidence Rating Level: 2 (Good) Adrenocortical carcinomas (ACC) are rare and typically carry a poor prognosis, with the majority of patients presenting...

Atopic dermatitis, a common disorder in the pediatric population, is associated with pruritus that is often worse at night and, thus, can interfere with sleep. This longitudinal cohort study aimed to assess whether active atopic dermatitis impacts sleep duration and quality, and to examine the association between severity of...

1. The results of this study suggested that the prevalence of atopic dermatitis increased with age among a U.K. adult primary care population. 2. The rates of active eczema were found to be highest among children and older adults. Evidence Rating Level: 2 (Good) Study Rundown: Atopic dermatitis, more commonly known as...

 1. The majority of patients using pimecrolimus cream (PIM, 52.6%) or topical corticosteroids (TCS, 50.5%) for the treatment of mild to moderate atopic dermatitis were cleared of manifestations of the disease by week 3 of use. 2. No significant differences in adverse effects and safety or changes in immunity were...

In this section, we highlight the key high-impact studies, updates, and analyses published in medicine during the past week. Randomized Assessment of Rapid Endovascular Treatment of Ischemic Stroke With current ischemic stroke treatment options, approximately 60 to 80% of patients suffering from a stroke involving the proximal vessel occlusion in the...

1. Allergic diseases, such as eczema and asthma, were significantly less prevalent in children whose parents washed dishes by hand rather than by machine. 2. Parents who reported cooking fermented foods and food from farms also had children with significantly decreased odds of developing allergic disease. Evidence Rating Level: 2 (Good)...

Originally published by Harvard Health. What Is It? Dermatitis is a skin inflammation. Eczema is the most common type of dermatitis. Eczema first appears as an episode of itching and redness of the skin. You also may have tiny bumps or blisters. When eczema develops into a long-term condition, it is called chronic eczema....