Tag: fluid replacement

1. There was no association found between positive fluid balance at the time of discharge and readmission at 30 days post-discharge in non-critically ill patients hospitalized for sepsis. Evidence Rating Level: 2 (Good) Study Rundown: Evidence suggests that the administration of intravenous fluids in patients hospitalized for sepsis is associated with...
1. No significant difference was found in neurological function recovery measured by extended Glasgow scale score in patients with moderate to severe traumatic brain injury 6-months after treatment with either continuous hypertonic saline or current care protocol. 2. No significant different in 6- month mortality was found between continuous hypertonic...
1. Among patients at increased risk for complications undergoing abdominal surgery, those randomized to perioperative fluid restriction did not have increased disability-free survival at one year compared to patients who received liberal perioperative fluid management. 2. Patients managed with fluid restriction experienced higher rates of acute kidney injury. Evidence Rating Level:...
Image: PD 1. Hospitalized children receiving hypotonic maintenance intravenous fluids (mIVF) were more likely to develop hyponatremia when compared to patients receiving isotonic mIVF. 2. No differences in incidence of hypernatremia were reported when comparing hypotonic to isotonic mIVF. Evidence Rating Level: 1 (Excellent) Study Rundown: Electrolyte imbalances, particularly concerning sodium, are common...
Feb 19th - In a study published today, hydroxyethyl starch use in fluid resuscitation associated with an increased risk of mortality. Image: PD 1. Hydroxyethyl starch use in fluid resuscitation associated with an overall mortality risk ratio of 1.07. 2. Excluding controversial Boldt et al studies, hydroxyethyl starch  is associated with an...
Classics Series, Landmark Trials in Medicine
1. There was no significant difference in 28-day mortality when comparing albumin and normal saline for fluid resuscitation in the intensive care setting. 2. Compared to normal saline, fluid resuscitation with albumin did not yield any significant benefits in terms of secondary outcomes (i.e., length of ICU/hospital stay, duration of...