Tag: High Blood Pressure

1. Regardless of cardiovascular disease history and baseline blood pressure, a 5 mmHg reduction in systolic blood pressure reduced relative risk of major cardiovascular events by 10%. 2. These findings support considering antihypertensive medications for patients with increased cardiovascular risk, even those who are normotensive at baseline.  Evidence Rating Level: 1...
1. Amongst the five examined classes of antihypertensive medications (ACE Inhibitors, ARBs, beta blockers, calcium-channel blockers, and thiazide diuretics), none were associated with a substantial increase in likelihood of COVID-19. Evidence Rating: 2 (Good) Infection of host cells by SARS-CoV-2 is mediated via an interaction with membrane-bound angiotensin-converting enzyme (ACE) 2,...
1. While chlorthalidone is the recommended thiazide diuretic treatment for hypertension, it has no added benefits compared to hydrochlorothiazide and has significantly worse safety profile. Evidence Rating Level: 1 (Excellent) The American College of Cardiology/American Heart Association hypertension guideline reported in 2017 that the recommended thiazide diuretic treatment for hypertension is currently...
The prevalence of hypertension is rapidly increasing in low-income and middle-income countries (LMICs). To effectively target interventions and monitor progress in hypertension care, it is essential to determine country-specific deficiencies in the hypertension care continuum. However, estimates of health system performance in hypertension care from nationally representative studies in...
1. In this randomized controlled trial, intensive blood pressure lowering in elderly patients reduced the risk of developing Mild Cognitive Impairment (MCI) compared to standard blood pressure lowering. 2. While there was no difference in the risk of dementia between groups, the trial was terminated early due to observed cardiovascular...
Originally published by Harvard Health. What Is It? Blood pressure has two components: Systolic pressure is the top number. It represents the pressure the heart generates when it beats to pump blood to the rest of the body. Diastolic pressure is the bottom number. It refers to the pressure in the blood vessels between...