Tag: hydrochlorothiazide

1. While chlorthalidone is the recommended thiazide diuretic treatment for hypertension, it has no added benefits compared to hydrochlorothiazide and has significantly worse safety profile. Evidence Rating Level: 1 (Excellent) The American College of Cardiology/American Heart Association hypertension guideline reported in 2017 that the recommended thiazide diuretic treatment for hypertension is currently...
1. While chlorthalidone is the recommended thiazide diuretic treatment for hypertension, it has no added benefits compared to hydrochlorothiazide and has significantly worse safety profile. Evidence Rating Level: 1 (Excellent) The American College of Cardiology/American Heart Association hypertension guideline reported in 2017 that the recommended thiazide diuretic treatment for hypertension is...
1. In this randomized, controlled trial, patients without cardiovascular disease randomized to receive a polypill containing atorvastatin, amlodipine, losartan, and hydrochlorothiazide experienced greater reductions in systolic blood pressure and low-density lipoprotein (LDL) cholesterol over 12 months compared to patients who received usual-care. 2. Polypill patients reported increased rates of myalgia,...
1. In this randomized, controlled trial, patients without cardiovascular disease randomized to receive a polypill containing atorvastatin, amlodipine, losartan, and hydrochlorothiazide experienced greater reductions in systolic blood pressure and low-density lipoprotein (LDL) cholesterol over 12 months compared to patients who received usual-care. 2. Polypill patients reported increased rates of myalgia,...
1. Black African patients with hypertension randomized to multiple two-drug combinations experienced greater blood pressure control when treated with amlodipine plus either hydrochlorothiazide or perindopril compared to those treated with perindopril plus hydrochlorothiazide. 2. Adverse event rates were similar in all three treatment groups. Evidence Rating Level: 1 (Excellent)   Study Rundown:...