Tag: iron

1. Intravenous iron prior to major abdominal surgery in anemic patients was not associated with decreased need for blood transfusions post-operation. 2. Preoperative intravenous iron did reduce the risk of readmission to hospital due to postoperative complications in anemic patients. Evidence Rating Level: 1 (Excellent) Study Rundown: Preoperative anemia is a common...
1. Certain dietary supplements, including vitamin B12, iron and omega-3 fatty acids, may negatively impact disease-free survival and overall survival in breast cancer patients undergoing chemotherapy Evidence Rating Level: 2 (Good) While the use of dietary supplements during cancer treatment is not uncommon, there is little data available to support current...
Chronic kidney disease (CKD)-related anemia is associated with significant morbidity, and remains undertreated worldwide. Adequate treatment of CKD-related anemia is associated with reduced transfusion rates and improved clinical outcomes. Roxadustat is a hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitor that stabilizes HIF-alpha subunits, resulting in increased transcriptional activity and functional...
1. Patients undergoing maintenance hemodialysis experienced fewer serious adverse events if treated proactively with high-dose intravenous iron sucrose compared to patients reactively treated with low-dose iron sucrose. 2. Higher doses of erythropoiesis-stimulating agents were utilized more in the low-dose iron group compared to the high-dose group. Evidence Rating Level: 1 (Excellent)       Study...
1. Compared to no supplementation, low-dose iron supplementation reduced time to 80% recovery of pre-donation hemoglobin concentration in blood donors. 2. This effect was seen regardless of sex or low or high levels of pre-donation ferritin. Evidence Rating Level: 1 (Excellent)  Study Rundown: Blood donors experience a drop in hemoglobin levels upon...
Image: PD 1. Daily iron supplementation in 2- to 5-year-olds increases hemoglobin and ferritin levels, though there is insufficient data to infer impact on iron deficiency anemia.  2. Supplementation has no effect on physical growth or morbidity from infectious causes. 3. Further data are needed to assess effects of daily iron supplementation...