Tag: Kawasaki disease

1. Severe acute respiratory syndrome coronavirus 2 infection increases the rate of Kawasaki disease in children. 2. Individuals with severe Kawasaki disease were more likely to have myocarditis, require combination therapy with inotrope treatment, and require admission to the intensive care unit. Evidence Rating Level: 2 (Good) Study Rundown: Viral disease is...
1. Severe acute respiratory syndrome coronavirus 2 infection increases the rate of Kawasaki disease in children. 2. Individuals with severe Kawasaki disease were more likely to have myocarditis, require combination therapy with inotrope treatment, and require admission to the intensive care unit. Evidence Rating Level: 2 (Good) Study Rundown: Viral disease is...
1. Findings from a cohort in Bergamo, Italy indicate a roughly 30-fold increase in the incidence of Kawasaki-like disease associated with the SARS-CoV-2 outbreak. 2. Pediatric patients diagnosed with Kawasaki-like disease post COVID-19 were more likely to have a more severe form of the disease, and had higher rates of...
1. Findings from a cohort in Bergamo, Italy indicate a roughly 30-fold increase in the incidence of Kawasaki-like disease associated with the SARS-CoV-2 outbreak. 2. Pediatric patients diagnosed with Kawasaki-like disease post COVID-19 were more likely to have a more severe form of the disease, and had higher rates of...
Early estimates of the indirect effects of the COVID-19 pandemic on maternal and child mortality in low-income and middle-income countries: a modelling study 1. In three separate models, it was found that the combination of decreased health care access, food availability, and the economic impacts (both intentional and unintentional) of...
1. In this meta-analysis of available comparative studies, use of corticosteroids as adjunctive therapy to IVIG and aspirin in Kawasaki disease was associated with a lower risk of coronary artery abnormality and earlier defervescence compared to IVIG/ASA alone. 2. In subgroup analysis the earlier timing of steroid therapy had lower...
1. Results of this retrospective study revealed that children diagnosed with Kawasaki disease often have a concurrent respiratory viral infection detectable by polymerase chain reaction (PCR). 2. Concurrent detection of a respiratory virus by PCR does not appear to be linked to the clinical presentation or outcomes of children with...

Patient Basics: Kawasaki Disease

Originally published by Harvard Health. What Is It? Kawasaki disease is a rare illness that typically strikes children younger than age 5. It is also known as mucocutaneous lymph node disease. Kawasaki disease is a mysterious illness of unknown cause, although some scientists suspect that the cause may be an infection...
Image: CC/Wiki. Coronary Aneurysm. 1. Five percent of young adults with childhood Kawasaki Disease had persistent coronary aneurysms.  2. Similar rates of acute cardiovascular events at age ≥ 15 years were noted in those with and without childhood Kawasaki Disease.  Evidence Rating Level: 2 (Good)  Study Rundown: Kawasaki Disease (KD) affects medium-sized blood...
Classics Series, Landmark Trials in Medicine
Image: PD 1. Children with Kawasaki disease treated with a combined regimen of aspirin and intravenous gamma globulin had significantly lower rates of coronary artery aneurysms when compared to those receiving aspirin only. 2. Children treated with the combined regimen had significantly shorter fevers and a greater decrease in inflammatory markers...