Tag: MACE

Patients with colorectal cancer (CRC) are 2-4 times more likely to develop cardiovascular disease, as compared to individuals without a history of cancer. With survival rates increasing significantly over the last 4 decades, this has important implications in patients that are now more susceptible to competing causes of morbidity...
Association between incidence exposure to benzodiazepines in early pregnancy and risk of spontaneous abortion Previous studies have shown that benzodiazepine use in early pregnancy is associated with spontaneous abortion (SA). The association between specific benzodiazepines and the risk of SA, however, has not been investigated. In this nested case-control study...
1. Among patients with type 2 diabetes and established or multiple risk factors for cardiovascular disease (CVD), dapagliflozin was noninferior but did not significantly reduce the rate of major adverse cardiovascular events (MACE) compared to placebo. 2. Dapagliflozin significantly reduced the hospitalization rates for heart failure compared to placebo in...
1. In this randomized controlled trial, medication vouchers were associated with a small increase in patient-reported persistence with P2Y12 inhibitors for patients who had suffered a myocardial infarction (MI). 2. Medication vouchers were not associated with reduced major adverse cardiovascular events (MACE) in these patients. Evidence Rating Level: 1 (Excellent)       Study Rundown: Antiplatelet therapy,...
1. In this randomized controlled trial, medication vouchers were associated with a small increase in patient-reported persistence with P2Y12 inhibitors for patients who had suffered a myocardial infarction (MI). 2. Medication vouchers were not associated with reduced major adverse cardiovascular events (MACE) in these patients. Evidence Rating Level: 1 (Excellent)       Study Rundown:...
1. After a median follow-up of 4.9 years, patients with elevated triglyceride levels despite statin use treated with icosapent ethyl had a lower risk of cardiovascular adverse events compared to patients in a placebo group. 2. Hospitalization for atrial fibrillation or flutter occurred in more patients treated with icosapent ethyl...
1. A significant reduction in major cardiac events among elderly patients was seen in the liraglutide treatment group. 2. The risk reduction of adverse cardiac events in the liraglutide treatment group seemed to vary with age.  Evidence Rating Level: 2 (Good) Study Rundown: Type 2 diabetes mellitus (T2DM) continues to increase in prevalence...