Tag: mastectomy

Nipple-sparing mastectomy (NSM) in the setting of breast cancer preserves the nipple-areola complex (NAC) and breast skin envelope. While previous studies have shown that NSM is an acceptable surgical option in select patients with breast cancer, there is limited long-term outcomes data for this approach. In this retrospective cohort...
1. Continuous postoperative levobupivacaine infusion into the surgical site was associated with less pain and decreased consumption of analgesics following modified radical mastectomy. 2. Patients in the levobupivacaine group reported high levels of satisfaction with no change in rates of nausea and vomiting. Evidence Rating Level: 1 (Excellent) Study Rundown: The use...
1. From 1998 to 2011, there was a substantial increase in the use of bilateral mastectomy for the treatment unilateral early-stage breast cancer in California. 2. While unilateral mastectomy demonstrated the highest mortality rates of the three surgical treatment options examined, bilateral mastectomy was not associated with lower mortality...
In this section, we highlight the key high-impact studies, updates, and analyses published in medicine during the past week. Effects of Extended-Release Niacin with Laropiprant in High-Risk Patients Despite lack of evidence of overall benefit, niacin has been increasingly used to help lower LDL cholesterol and raise HDL cholesterol, modifiable risk...
1. In women with newly diagnosed breast cancer, contralateral prophylactic mastectomy conferred a minimal increase in projected life expectancy, between 1 and 7 months.  2. The survival benefit was slightly greater in younger women with stage I, ER-negative breast cancer, however the 20-year overall survival difference was still <1%.  Evidence Rating...
1. Both prophylactic and therapeutic nipple-sparing mastectomies were associated with low locoregional occurrence or recurrence.  2. Occurrence or recurrence of cancer was not found within the preserved nipple-areolar complex.  Evidence Rating Level: 2 (Good)             Study Rundown: While prevalence of nipple-sparing mastectomies (NSM) is increasing, concern exists that...
Image: PD 1. Breast-conserving therapy (BCT) is associated with greater overall and disease-specific survival benefit than mastectomy for early-stage breast cancer, regardless of age and tumor hormone receptor status. 2. The benefit of BCT is greatest for women older than 50 years with HR-positive disease. Among breast cancer treatment options, there has...