Tag: migraine

1. In this cohort of women, those who experienced migraines with aura were associated with an increased adjusted incidence rate for major cardiovascular diseases (CVD) compared to those with migraines without aura or no migraines. 2. After diabetes and smoking, migraines with aura were found to have the highest CVD...
1. For patients with medication overuse headache, withdrawal and preventive medication was more effective at reducing headache than other strategy alone. Evidence Rating: 1 (Excellent) Medication overuse headache (MOH) affects more than 60 million people globally and is considerably disabling. Although current guidelines recommend withdrawal of medication and preventive medication usage,...
1. In this multicenter study involving adult patients in the United States with a history of migraine, ubrogepant was shown to be more effective than placebo in providing freedom from pain and alleviating the most bothersome symptom within two hours. 2. Doubling the dosage of ubrogepant resulted in limited efficacy...
1. In this multicenter study involving adult patients in the United States with a history of migraine, ubrogepant was shown to be more effective than placebo in providing freedom from pain and alleviating the most bothersome symptom within two hours. 2. Doubling the dosage of ubrogepant resulted in limited efficacy...
1. Patients with migraine treated with rimegepant during an acute event had resolution of pain and their most bothersome symptoms 2 hours after onset more frequently than patients treated with placebo. 2. Incidence of adverse events were similar for patients treated with either rimegepant or placebo. Evidence Rating Level: 1 (Excellent)...
1. Patients with migraine treated with rimegepant during an acute event had resolution of pain and their most bothersome symptoms 2 hours after onset more frequently than patients treated with placebo. 2. Incidence of adverse events were similar for patients treated with either rimegepant or placebo. Evidence Rating Level: 1 (Excellent)...
1. In this randomized controlled trial, Fremanezumab slightly decreased the amount of headache free days in those with episodic migraines compared to placebo. 2. Fremanezumab was associated with greater mild injection site reactions but not more serious adverse events. Evidence Rating: 1 (Excellent) Study Rundown: Fremanezumab, an anti-Calcitonin Gene-Related Peptide (anti-CGRP), has...
1. Monthly injections of erenumab were associated with reduced migraine frequency, decreased use of acute migraine medication, and decreased migraine burden on daily activities compared to placebo among patients with episodic migraines. 2. The overall safety profile of erenumab in this trial was comparable to placebo with regards to...
1. Patients with chronic migraine receiving fremanezumab had significantly fewer migraines and headaches than those receiving placebo after 12 weeks of treatment. 2. Injection-site reactions, including pain and induration, were the most frequently reported adverse event in both fremanezumab and placebo treated patients. Evidence Rating Level: 1 (Excellent) Study Rundown: Migraine is...
1. In this case-control study of ischemic strokes in younger adults, stroke from cervical artery dissection (CEAD) was associated with increased prevalence of history of migraine compared to other causes of ischemic stroke. 2. The majority of the observed association was driven by the increased prevalence of migraine without aura...