Tag: mortality

1. Both CA125 serum and transvaginal ultrasound annual screening did not significantly reduce deaths due to ovarian or tubal cancer compared to no annual screening. 2. The incidence of stage III-IV disease was decreased in the CA125 screening group compared to no annual screening. Evidence Rating Level: 1 (Excellent) Study Rundown: Ovarian cancer has a...

1. Positive fecal immunochemical test (FIT) results were associated with increased incidences of ischemic stroke, myocardial infarction, and all-cause mortality. Evidence Rating Level: 2 (Good) While fecal immunochemical tests (FIT) is a commonly used and effective screening tool for colorectal cancer (CRC), their clinical use in detecting other diseases is poorly known....

1. Patients with chronic obstructive pulmonary disease who were prescribed inhaled corticosteroids had an increased risk of COVID-19-related deaths compared to those on long-acting beta-agonist and long-acting muscarinic antagonist dual therapy. 2. Among asthma patients, a high-dose, but not low- or medium-dose, of inhaled corticosteroids was associated with an increased risk...

1. Children with obesity were at greater risk of mortality in early adulthood than a population-based comparison group, suggesting that risks begin earlier than later adulthood. 2. Deaths due to suicide and self-injury are also common in this group, warranting clinical consideration at a primary care level. Evidence Rating Level: 2 (Good) The impacts...

1. Sepsis bundles were not significantly associated with decreased risk of mortality or reduced vasopressor treatment time in community- or hospital-onset sepsis. 2. Components of the SEP-1 bundle, such as broad-spectrum IV antibiotic treatment and lactate levels were associated with improved outcomes in this population. Evidence Rating Level: 2 (Good) Sepsis bundles, or protocols...

1. Children with obesity were at greater risk of mortality in early adulthood than a population-based comparison group, suggesting that risks begin earlier than later adulthood. 2. Deaths due to suicide and self-injury are also common in this group, warranting clinical consideration at a primary care level. Evidence Rating Level: 2 (Good) The impacts...

1. Findings from this cohort study suggest that diets including processed meat, unprocessed, or poultry have significant associations with incidence of cardiovascular disease while fish do not 2. Processed meats and unprocessed red meats have significant association with all-cause mortality while poultry and fish did not Evidence Rating: 2 (Good) The concept...

Dexamethasone treatment for the acute respiratory distress syndrome: a multicentre, randomised controlled trial 1. Study findings suggest that early administration of intravenous dexamethasone during acute respiratory distress syndrome may decrease duration of mechanical ventilation and mortality rates. Evidence Level: 1 (Excellent) Acute respiratory distress syndrome (ARDS), characterized by acute hypoxemic respiratory failure...