Tag: multidrug-resistant organisms

1. A randomized control trial of patients with multidrug resistant tuberculosis found that shorter treatment regimens were noninferior to longer treatment regimens currently recommended by the WHO. 2. Severe adverse events were noted in both arms including death, QT interval prolongation and increases in alanine transaminase (ALT) levels. Evidence Rating Level:...
1. A randomized control trial of patients with multidrug resistant tuberculosis found that shorter treatment regimens were noninferior to longer treatment regimens currently recommended by the WHO. 2. Severe adverse events were noted in both arms including death, QT interval prolongation and increases in alanine transaminase (ALT) levels. Evidence Rating...
Universal decontamination in the intensive care unit (ICU) has led to success in reducing bloodstream infections and infections with multi-drug resistant organisms. In this cluster-randomized trial of 53 hospitals, a similar protocol of universal decontamination using daily chlorhexidine bathing, as well as the administration of muciprocin for known methicillin-resistant...
Veverimer Versus Placebo in Patients with Metabolic Acidosis Associated with Chronic Kidney Disease: a Multicenter, Randomized, Double-Blind, Controlled, Phase 3 Trial Chronic metabolic acidosis is often seen in patients with chronic kidney disease (CKD), and results from an inability to excrete metabolically produced acid. This, in turn, is associated with...