Tag: myocardial infarction

Ischemic heart disease, the most common cause of morbidity and mortality worldwide, has many modifiable and non-modifiable risk factors, including several external factors. This retrospective observational study aimed to investigate circadian rhythms, major sports events, and national holidays as potential triggers of myocardial infarction. Investigators reviewed 283,014 cases of...
Pegbelfermin (BMS-986036), a PEGylated Fibroblast Growth Factor 21 Analogue, in Patients with Non-Alcoholic Steatohepatitis: A Randomised, Double-Blind, Placebo-Controlled, Phase 2a Trial Non-alcoholic steatohepatitis (NASH), the most common chronic liver disease in the United States, puts patients at increased risk of developing cirrhosis and hepatocellular carcinoma. Patients with NASH are also...
The influence of certain weather trends on the incidence of myocardial infarction (MI) has not been well established. In this prospective population-based study, investigators obtained daily weather data from the Swedish Meteorological and Hydrological Institute for 274,029 MIs in order to determine whether an association exists between weather and...
Patients with schizophrenia have a shortened life expectancy of 15-20 years compared with the general population, with excess cardiac mortality contributing to this difference. Interestingly, no studies have evaluated the impact of cardioprotective medications after myocardial infarction (MI) in this patient population. In this nationwide cohort study, investigators examined...
1. A positive association was found between the antiphospholipid antibody immunoglobulin G and first-time myocardial infarctions in study patients. 2. No relationships were observed between the antiphospholipid antibody immunoglobulin M or A in these patients. Evidence Rating Level: 2 (Good) Study Rundown: Antiphospholipid syndrome (APS) is an autoimmune condition characterized by hypercoagulability....
1. Patients with an acute myocardial infarction (MI) and ejection fraction less than 35% did not have reduced incidence of arrhythmic death within 90 days of the index MI compared to control patients. 2. Incidence of nonarrythmic death was also similar within 90 days of MI for patients in the...
1. In this meta-analysis of available randomized clinical trials, use of aldosterone antagonist therapy in patients with preserved ejection fraction following ST-elevation myocardial infarction (STEMI) was associated with reduction in overall mortality. 2. Use of aldosterone agonist was linked to a small increase in serum potassium and no overall difference...
1. Patients with the highest Aβ40 also had the worst non-ST-segment elevation acute coronary syndrome (NSTE-ACS) risk profile. 2. Greater all-cause mortality was observed in patients with higher circulating Aβ40. Evidence Rating Level: 2 (Good) Study Rundown: Acute coronary syndrome (ACS) remains a major cause of morbidity and mortality. Identifying predictors and...
1. In a modern cohort of patients with readily available primary percutaneous coronary intervention, woman experienced greater mortality rates then men following ST-elevation myocardial infarction. 2. The greater mortality was only apparent in younger patients, under the age of 60 years. Evidence Rating Level: 2 (Good) Study Rundown: Prior studies have demonstrated...
1. A locally adapted quality improvement tool kit was not sufficient to improve the rate of 30-day major adverse cardiovascular events in patients with acute MI in Kerala, India Evidence Rating Level: 1 (Excellent) Study Rundown: Ischemic heart disease represents the leading cause of deaths world-wide, and while developed countries have...