Tag: neonatology

Classics Series, Landmark Trials in Medicine
1. Among term infants with neonatal encephalopathy associated with mild EEG changes, those randomized to head cooling had a reduced incidence of death and severe neurodevelopmental disability compared to infants randomized to conventional care. Original Date of Publication: January 2005 Study Rundown: Hypoxic-ischemic encephalopathy (HIE) is a highly morbid cause of...
1. In addition to commonly used sucrose, non-pharmacologic methods of neonatal pain control such as radiant warmth are being explored.  2. Healthy, term neonates receiving radiant warmth in addition to sucrose, compared to neonates receiving sucrose only, showed fewer autonomic responses and facial features suggestive of pain during a routine...
1. Common factors associated with infant deaths in neonatal intensive care units (NICU) varied according to gestational age. 2. A total of 31% of deaths were associated with potentially modifiable risk factors, with delivery at a health care facility without proper support being the most common. Study Rundown: It is known...
Classics Series, Landmark Trials in Medicine
1. Among women with imminent delivery between 24 and 31 weeks gestation, those randomized to receive magnesium sulfate experienced a decreased risk of moderate or severe cerebral palsy. 2. Risk of fetal death did not differ between groups. Original date of publication: August 28, 2008 Study Rundown: Cerebral palsy, the leading cause...
1. The implantation of an embryo, created through in vitro fertilization, into a transplanted human uterus resulted in normal pregnancy of nearly 32 weeks. 2. The transplant patient experienced three cases of mild rejection that were treated with corticosteroids, and pre-eclampsia at 32 weeks that resulted in a cesarean section...
1. Among infants born at > 35 weeks, the majority of neonates studied required postresuscitation care (PRC) including ventilator support, parenteral nutrition, or prolonged intensive care stay regardless of short (< 1 min) or prolonged (≥ 1 min) positive pressure ventilation (PPV) at birth. 2. Placental abruption, preterm and small...
1. Single-family room (SFR) model of care in the NICU improved medical and neurodevelopmental outcomes in infants. 2. Increased developmental support and maternal support in the SFR model were identified as mediating factors for improved outcomes. Evidence Rating Level: 2 (Good) Study Rundown: Single-family rooms (SFR) have increasingly replaced the traditional open-bay...
1. Girls born before 34 weeks gestation were found to have higher blood pressures at age 16 than those born after 37 weeks. Boys born preterm had worse cholesterol levels in adolescence when compared to males born at term. 2. A dose-response relationship was observed with gestational age and health...
1. Parents who used a midwife to deliver their child and those who delivered at home or in a birthing center were at a significantly increased risk of refusing to provide their newborn with vitamin K prophylaxis. 2. Children who did not receive vitamin K prophylaxis at birth had an increased...
Image: PD 1. This systematic review did not find an association between omega-3 fatty acid supplementation and decreased incidence of bronchopulmonary dysplasia (BPD) among neonates. 2. In a subset of extremely premature infants, effects of omega-3 fatty acid supplementation were still non-significant, but trended towards a lower risk of BPD and...