Tag: nonsteroidal anti-inflammatory drug (NSAID)

Anemia is associated with the risk of Crohn’s disease, not ulcerative colitis: A nationwide population-based cohort study 1. Anemia increased the risk of development of Crohn’s disease, inversely to hemoglobin concentration 2. Anemia was not associated with an increased risk of ulcerative colitis. Evidence Rating Level: 2 (Good) Though inflammatory bowel disease (IBD)...

1. Ixekizumab, an IL-17 inhibitor, elicits disease response in patients with non-radiographic active axial spondyloarthritis who have failed treatment with NSAIDs. Evidence Rating Level: 1 (Excellent) Axial spondyloarthritis is a chronic inflammatory disease of the axial skeleton that is typically treated with non-steroidal anti-inflammatory drugs (NSAIDs). Biologic disease-modifying anti-rheumatic drugs (bDMARDs) have...

1. Ixekizumab, an IL-17 inhibitor, elicits disease response in patients with non-radiographic active axial spondyloarthritis who have failed treatment with NSAIDs. Evidence Rating Level: 1 (Excellent) Axial spondyloarthritis is a chronic inflammatory disease of the axial skeleton that is typically treated with non-steroidal anti-inflammatory drugs (NSAIDs). Biologic disease-modifying anti-rheumatic drugs (bDMARDs) have...

1. Children aged ≤10 years who had overdosed on opioids were more than 2 times more likely to have a mother with opioid prescriptions than one with prescriptions for non-steroidal anti-inflammatory drugs (NSAIDs).  2. Codeine, methadone, and oxycodone were the top 3 maternal opioid prescriptions implicated in pediatric opioid toxicity. Evidence Rating:...

  1. Compared with placebo, patients who took Tramadol or Celecoxib experienced significantly reduced pain during and after hysteroscopy. 2. There was no significant difference in pain scores between the Tramadol and Celecoxib groups. Evidence Rating Level: 1 (Excellent) Study Rundown: Hysteroscopy is the gold standard for diagnosing focal endometrial pathology that causes...

1. This study found that the regular use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), or both was associated with a decreased risk of colorectal cancer. 2. Two single nucleotide polymorphisms (SNPs) were highly correlated with the association between NSAIDs and colon cancer risk. Evidence Rating Level: 3 (Average) Study Rundown: Genetic sequencing...

In this section, we highlight the key high-impact studies, updates, and analyses published in medicine during the past week. 6- Versus 24-Month Dual Antiplatelet Therapy After Implantation of Drug-Eluting Stents in Patients Nonresistant to Aspirin: The Randomized, Multicenter ITALIC Trial Current national society guidelines recommend 12 months of dual antiplatelet therapy...