Tag: pancreatitis

1. Dose escalation of rectal indomethacin does not provide any benefit in preventing pancreatitis in high-risk patients post-endoscopic retrograde cholangiopancreatography. Evidence Rating Level: 1 (Excellent) Pancreatitis is the most frequent and concerning complication of endoscopic retrograde cholangiopancreatography (ERCP). Use of rectal non-steroidal anti-inflammatory drugs (NSAIDs) such as indomethacin and diclofenac peri-procedurally...
1. Dose escalation of rectal indomethacin does not provide any benefit in preventing pancreatitis in high-risk patients post-endoscopic retrograde cholangiopancreatography. Evidence Rating Level: 1 (Excellent) Pancreatitis is the most frequent and concerning complication of endoscopic retrograde cholangiopancreatography (ERCP). Use of rectal non-steroidal anti-inflammatory drugs (NSAIDs) such as indomethacin and diclofenac peri-procedurally...
Long-term impact of an educational antimicrobial stewardship programme in primary care on infections caused by extended-spectrum β-lactamase-producing Escherichia coli in the community: an interrupted time-series analysis. 1. A multi-modal antimicrobial stewardship program in primary care focused on individual educational interviews may improve antibiotic prescription practices and lead to sustained reductions...
1. Triglyceride levels in familial chylomicronemia patients were notably reduced when treated with the apolipoprotein C-III antisense mediated inhibitor volanesorsen compared to placebo treated patients. 2. Patients treated with volanesorsen experienced thrombocytopenia and injection site reactions, and a notable number of volanesorsen patients discontinued the trial due to treatment related...
1. Triglyceride levels in familial chylomicronemia patients were notably reduced when treated with the apolipoprotein C-III antisense mediated inhibitor volanesorsen compared to placebo treated patients. 2. Patients treated with volanesorsen experienced thrombocytopenia and injection site reactions, and a notable number of volanesorsen patients discontinued the trial due to treatment related...
1. Early feeding may reduce hospital stay in patients with mild pancreatitis. 2. Early feeding was not associated with adverse events and may help reduce gastrointestinal symptoms. Evidence Rating Level: 1 (Excellent) Study Rundown: Acute pancreatitis is a common disease of the gastrointestinal tract with increasing costs and incidence worldwide. Recent studies...
1. This prospective cohort study, conducted in Copenhagen, found that mild-to-moderate levels of non-fasting hypertriglyceridemia, from 177 mg/dL (2 mmol/L) and above, were associated with increased risk of acute pancreatitis. 2. These increases in risk for acute pancreatitis were greater than the corresponding risk of myocardial infarction within the same...
1. In a retrospective review of over 5000 children with acute lymphoblastic leukemia (ALL) who received asparaginase induction therapy, independent clinical risk factors for pancreatitis include Native American ancestry, older age, and higher cumulative doses of asparaginase. 2. Patients with specific mutations to CPA2 gene were at a significantly higher...