Tag: pediatric oncology

1. Three quarters of parents of children with a cancer diagnosis report greater optimism about their child’s prognosis than the child’s physician. 2. Parents who valued implicit prognostic information, such as a general sense of oncologist’s perception of child wellbeing, or spiritual information were significantly less accurate in estimating their...
1. More intense interventions at the end-of-life for children with cancer was associated with a bimodal age distribution (children younger than 5 and older than 15) and with hematologic malignancies. 2. African American, Asian American, and Hispanic children were more likely to die in the hospital, a marker of higher...
1. Over the past 40 years there has been a reduction in the average radiation doses given to children with certain cancers. Rates of subsequent cancers in these patients have likewise diminished. Evidence Rating Level: 2 (Good) Study Rundown: While radiation therapy (RT) is the cornerstone of treatment for a number...
1. The overall incidence of ovarian mass malignancy was low. 2. Fine needle aspiration cytology (FNAC) had low sensitivity and high specificity for detecting malignancy in children and adolescents with ovarian masses. Evidence Rating Level: 2 (Good) Study Rundown: Ovarian masses in the pediatric population may represent cysts, benign growths or malignant...
1. In a prospective cohort of over 400 children with acute lymphoblastic leukemia treated with chemotherapy, hip MRI have high sensitivity and specificity for detecting glucocorticoid-induced osteonecrosis. 2. Use of screening in children older than 10 years of age within 1 year after initiation of glucocorticoids may delay and prevent...
1. In a retrospective review of over 700 childhood cancer survivors (CCS) treated with cranial radiotherapy, over 50% developed anterior pituitary dysfunction. 2. A significant number of CCS who developed growth hormone and sex-hormone deficiencies were not recognized, leading to serious cardiovascular and musculoskeletal morbidities. Evidence Rating Level: 3 (Average)   Study...