Tag: preeclampsia

1. Low-dose aspirin significantly reduced the incidence of preterm preeclampsia in women identified as high-risk for preeclampsia using a screening protocol that combined maternal factors with biochemical measurements at 11-13 weeks of gestation. 2. No significant differences in adverse outcomes were found in women given low-dose aspirin compared to placebo. Evidence...
1. Among women with gestational hypertension, those who breastfed had lower postpartum blood pressures than those who did not. 2. Breastfeeding was not associated with differences in postpartum blood pressure in women with preeclampsia or those with normotension in pregnancy. Evidence Rating Level: 1 (Excellent) Study Rundown: Hypertensive disorders of pregnancy, which...
  1. Preeclampsia is a partially understood condition in which circulating maternal serum levels of soluble fms-like tyrosine kinase 1 (sFlt-1) are increased and placental growth factor (PlGF) levels are decreased. 2. sFlt-PlGF ratios of 38 or lower had a negative predictive value of 99.3% for the outcome of no...
1. Women with pre-eclampsia randomized to magnesium experienced a greater than 50% reduction in eclampsia compared to women on placebo. Original Date of Publication: June 2002 Study Rundown: Pre-eclampsia is a multi-system hypertensive disorder of pregnancy associated with significant maternal morbidity and mortality. Worldwide, approximately 50 000-60 000 women die from...
1. Women with urinary tract infection (UTI) in the first or third trimester of pregnancy were more likely to develop preeclampsia. 2. UTI was associated with increased levels of placental growth factor (PIGF), which subsequently decreased among women who developed preeclampsia. Evidence Rating Level: 2 (Good)            Study Rundown: Preeclampsia is a disorder...
1. Aspirin therapy for high-risk women was associated with a lower prevalence of preeclampsia. 2. In women with preeclampsia, aspirin therapy was linked with a lower likelihood of early delivery. Evidence Rating Level: 2 (Good) Study Rundown: Preeclampsia, characterized by high blood pressures after 20 weeks of pregnancy, can occur in women...
1. Women who used an intrauterine device (IUD) were less likely to develop preeclampsia in subsequent pregnancies. 2. The protective effect of IUD use was observed in nulliparous women only. Evidence Rating Level: 3 (Average)        Study Rundown: Intrauterine devices (IUDs) are considered one of the most effective contraceptive methods,...
1. Women with preeclampsia were more likely to have a child diagnosed with autism spectrum disorder. 2. Women who experienced severe preeclampsia with placental insufficiency were more likely to have a child with developmental delay. Evidence Rating Level: 3 (Average)   Study Rundown: Autism spectrum disorder (ASD) and developmental delay (DD) are...
1. Vitamin D deficiency was associated with increased odds of developing preeclampsia. 2. An inverse dose-response relationship was observed between vitamin D levels and risk for preeclampsia. Evidence Rating Level: 3 (Average) Study Rundown: Preeclampsia is a hypertensive disorder of pregnancy, diagnosed when women at ≥20 weeks gestation develop a...
1. Use of low-dose aspirin was associated with a reduced risk for preeclampsia, intrauterine growth restriction and preterm birth in women at high risk for preeclampsia. 2. Low-dose aspirin was not associated with any appreciable harms during pregnancy. Evidence Rating Level: 1 (Excellent) Study Rundown: Preeclampsia is among the leading causes of...