Tag: pregnancy complications

1. The relative risk of a twin pregnancy amongst women who had undergone in vitro fertilization (IVF) compared with those who had not was 20.8 amongst a cohort of more than 16 million patients in China. 2. The most common adverse outcomes following IVF pregnancy were cesarean delivery, low birth...
1. Active management (methotrexate or uterine evacuation followed by methotrexate if needed) more frequently resulted in pregnancy resolution among patients with persisting pregnancy of unknown location compared to expectant management. 2. Treatment with empirical methotrexate versus uterine evacuation (with methotrexate as required) demonstrated similar efficacy in pregnancy resolution among women...
1. There was no significant difference with regard to diagnosis and treatment of pre-eclampsia, fetal growth restriction, and gestational diabetes between the telehealth integrated care and conventional models. 2. A significant reduction in the incidence of pre-term births among women in high-risk pregnancies was seen (-0.68% change per week). Evidence Rating...
1. Chemotherapy was associated with an increased risk of major congenital malformations in the initial 12 weeks of pregnancy. 2. These risks and the prevalence of incidental pregnancies concurrent to chemotherapeutic treatments emphasizes the importance of prenatal and perinatal counselling for women of child-bearing age with cancer. Evidence Rating Level: 2...
1. Over a mean follow-up period of 3.6 years, no significant association was detected between maternal influenza vaccination during pregnancy and early childhood health outcomes including pediatric asthma, neoplasms and sensory impairment. Evidence Rating: 2 (Good) Study Rundown: Vaccine hesitancy, particularly during pregnancy and early childhood, is a key issue that...
1. Counseling and behavioral interventions to limit excess gestational weight gain was associated with decreased risk of gestational diabetes, emergency cesarean delivery, macrosomia, and large for gestational age babies. 2. Behavioral interventions aimed at promoting healthy weight gain during pregnancy were also associated with modest reductions in mean gestational weight...
1. Dolutegravir-based antiretroviral therapy regimens effectively suppressed maternal viral load during pregnancy, supporting their use to prevent vertical transmission. 2. Dolutegravir, emtricitabine, and tenofovir alafenamide fumarate carried relatively low risk of adverse fetal outcomes. Evidence Rating Level: 1 (Excellent) Study Rundown: Initiation of antiretroviral therapy (ART) for pregnant women infected with HIV-1...
1. Systematic review of RCTs demonstrates reduced rate of early preterm birth (<34 weeks) for high-risk (previous spontaneous preterm birth, short cervix) singleton pregnancies with vaginal progesterone and intramuscular 17-hydroxyprogesterone caproate (17-OHPC). 2. Efficacy of vaginal progesterone and 17-OHPC may be more effective for women with short cervices.  Evidence Rating Level:...
1. Infants born to mothers who used medications for treatment of attention-deficit/hyperactivity disorder (ADHD) during pregnancy had increased risk of central nervous system (CNS) disorders, prematurity, and admission to the neonatal intensive care unit (NICU). 2. ADHD medication use during pregnancy was not associated with increased risk of neonatal mortality...
1. There has been concern about the linkage between lithium use during pregnancy and a risk of cardiac malformations, specifically Ebstein’s anomaly, with varying levels of association found in prior studies. 2. Using Medicaid data from over 1 million pregnancies, exposure to lithium during the first trimester was associated with...