Tag: pregnancy complications

1. Systematic review of RCTs demonstrates reduced rate of early preterm birth (<34 weeks) for high-risk (previous spontaneous preterm birth, short cervix) singleton pregnancies with vaginal progesterone and intramuscular 17-hydroxyprogesterone caproate (17-OHPC). 2. Efficacy of vaginal progesterone and 17-OHPC may be more effective for women with short cervices.  Evidence Rating Level:...
1. Infants born to mothers who used medications for treatment of attention-deficit/hyperactivity disorder (ADHD) during pregnancy had increased risk of central nervous system (CNS) disorders, prematurity, and admission to the neonatal intensive care unit (NICU). 2. ADHD medication use during pregnancy was not associated with increased risk of neonatal mortality...
1. There has been concern about the linkage between lithium use during pregnancy and a risk of cardiac malformations, specifically Ebstein’s anomaly, with varying levels of association found in prior studies. 2. Using Medicaid data from over 1 million pregnancies, exposure to lithium during the first trimester was associated with...
1. In a cohort of women with prior history of pregnancy loss, nausea and vomiting were associated with reduced risk of pregnancy loss. 2. There was also a trend towards decreased pre-implantation loss in this population as well. Evidence Rating Level: 2 (Good)        Study Rundown: Nausea and vomiting are...
1. Women with a history of hypertensive disorders of pregnancy have a small but significant increased risk of developing cardiomyopathy in the peri-partum period 2. This increased risk of cardiomyopathy persisted for more than five years after the most recent pregnancy Evidence Rating Level: 2 (Good)        Study Rundown: It...
1. Mean arterial pressure at follow-up was lower among women who had become pregnant. 2. A greater decrease in arterial stiffness was observed among women who had become pregnant. Evidence Rating Level: 2 (Good) Study Rundown: Many physiologic changes occur during pregnancy in order to support the development of a growing fetus....