Polymyxin B hemoperfusion unlikely to reduce mortality for sepsis
1. In this randomized controlled trial, hemoperfusion with polymyxin B resulted in similar 28-day mortality compared to sham hemoperfusion for ...
Tag: sepsis
Adjunctive glucocorticoid therapy does not lower mortality in septic shock
1. Patients with septic shock in the intensive care unit (ICU) undergoing mechanical ventilation and managed with adjunctive continuous hydrocortisone ...
Complex government-mandated sepsis performance measures not shown to improve survival
1. No moderate- or high-level evidence was found that SEP-1 or its hemodynamic interventions increase survival in septic adults. 2. ...
Systemic inflammatory response syndrome criteria may be more sensitive than quick sequential organ failure assessment for predicting mortality in patients with suspected infection
1. For predicting short-term mortality in patients with suspected infection, quick Sequential Organ Failure Assessment (qSOFA) had moderate specificity and ...
QI initiatives improve antibiotic initiation in bone marrow transplant patients
1. Increased education and process standardization led to a significant decrease in time to antibiotic administration among inpatient bone marrow ...
Quality improvement intervention decreases time to antibiotics in children with intestinal failure and fever
1. Increasing provider education and streamlining antibiotic order sets led to significantly decreased time to antibiotic administration in children with ...
Levosimendan does not improve sepsis-related outcomes: The LeoPARDS trial
1. No significant difference was observed in 28-day mean SOFA score or overall mortality in patients who received levosimendan vs. ...
Among sepsis survivors, primary care interventions not associated with improved mental health outcomes
1. Compared to standard care, 6 months of primary care interventions were not associated with any improvement in mental health-related ...
Sepsis associated with susceptibility to further infections and immunosuppression
1. Patients with sepsis were predisposed to ICU-acquisition of further infections. 2. Sepsis is associated with a degree of immunosuppression. ...
A new definition of sepsis
1. Sepsis, now defined as “life threatening organ dysfunction caused by a dysregulated host response to infection,” can be identified ...