Tag: Sirolimus (rapamycin)
Rapamycin inhibits intestinal tumor formation and growth [PreClinical]
1. Rapamycin (rapa) inhibited tumor initiation in Adenomatous polyposis coli gene (Apc)-deficient mouse intestinal epithelial cells, and enhanced survival in ...
Novel mTOR inhibitor may prolong heart transplant survival in mice
1. Chemotherapy agent AZD80559, a competitive mTOR inhibitor, suppressed T cell proliferation in vitro more effectively than Rapamycin. 2. Like ...
Sirolimus may prevent graft failure in patients with renal transplant for antiphospholipid syndrome
1. Antiphospholipid syndrome (APLS) in an autoimmune condition causing mechanical endothelial injury leading to activation of a pathway that triggers ...