Tag: skin cancer

The ideal surgical excision margin for patients with thick (>2 mm) localized cutaneous melanomas is unclear, where the risk of recurrence must be weighed against excess morbidity resulting from larger skin defects with wide excision. In this randomized controlled trial, 936 clinically staged patients were recruited and randomly assigned...
Association of HLA antigen mismatch with risk of developing skin cancer after solid-organ transplant Immunosuppressive agents reduce the risk of graft rejection in solid-organ transplant recipients. However, immunosuppressive regimens are not without risks, increasing the risk of cancer, a major source of morbidity and mortality. In particular, the risk of...
1. Behavioral interventions increase sun protection behavior but do not reduce sunburn or skin cancer outcomes in adults. 2. Behavior interventions lead to increased skin self-examinations but may lead to additional skin procedures without finding additional skin cancers. 3. The Task Force concluded that there is clear benefit to providing this counseling...
1. Treatment with a single treatment of topical fluorouracil cream reduced the long-term number of actinic keratoses (AKs) compared to those who had received cream alone. Evidence Rating Level: 1 (Excellent)       Study Rundown: AKs are highly prevalent among elderly patients and are associated with a significant cost and...
1. The total number of non-melanoma skin cancers (NMSC) in the US population was estimated to have increased to 5,434,193 in 2012 from 4,013,890 in 2006. Evidence Rating Level: 2 (Good)            Study Rundown: Non-melanoma skin cancer (NMSC), which includes both basal and squamous cell carcinomas, is the most...
1. In choosing a preferred modality for skin biopsy result notification, patients reported promptness of notification to be the most important consideration. Evidence Rating Level: 2 (Good) Study Rundown: With improvements in technology, there are new options for notification of skin biopsy results that now range from traditional in-person...
1. The risk for another non-melanoma skin cancer (NMSC) was significantly higher after a non-first NMSC diagnosis compared to the risk for another NMSC after a first-time NMSC diagnosis. Evidence Rating Level: 2 (Good) Study Rundown: NMSC – basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) – place...
1. Of the 125 colleges selected for this study, nearly half had indoor tanning facilities either on-campus or off-campus. Evidence Rating Level: 3 (Average) Study Rundown: Indoor tanning is well established as a risk factor for skin cancer, with some studies likening the association to smoking and lung cancer....
1. Patients with vitiligo had lower risk of having melanoma and non-melanoma skin cancers (NMSCs) than those without vitiligo. 2. Patients with vitiligo who had undergone UV phototherapy had an increased incidence of melanoma and NMSCs compared to patients with vitiligo who had not received phototherapy. Evidence Rating Level:...
1. Squamous Cell Carcinoma (SCC) and Basal Cell Carcinoma (BCC) displayed differing environmental and demographic etiologies, but development of both cancers were correlated with higher ambient ultraviolet radiation (UVR) levels.  2. Statistical models may accurately predict the incidence of SCCs and BCCs based on age group, sex, and ambient UVR.  Evidence...