Tag: staph aureus

1. Mupirocin was shown to have an overall primary decolonization efficacy of 95% when used to treat Staphylococcus aureus among infants <24 months old admitted to the neonatal intensive care unit (NICU). 2. Almost half of all treated patients who demonstrated primary decolonization and remained in the hospital at day 22 also...
1. Mupirocin was shown to have an overall primary decolonization efficacy of 95% when used to treat Staphylococcus aureus among infants <24 months old admitted to the neonatal intensive care unit (NICU). 2. Almost half of all treated patients who demonstrated primary decolonization and remained in the hospital at day...
1. In patients lacking any of the four high-risk criteria for Staphylococcus aureus infective endocarditis, including an indeterminate or positive TTE, community-acquired bacteremia, IV drug use, or a high-risk cardiac condition, a negative transthoracic echocardiogram effectively ruled out endocarditis. Evidence Rating Level: 2 (Good) Study Rundown: Staphylococcus aureus bacteremia (SAB) is...
1. Mice treated with a vaccine cocktail containing five S. aureus antigens (4C-Staph) had significantly fewer adverse outcomes following S. aureus infection as compared to vaccines containing individual antigens. 2. Addition of a small molecule immune potentiator to 4C-Staph further significantly increased viability in mice treated with lethal doses of...
1. In response to infection by Staphylococcus aureus (S. aureus), dermal cell populations expanded and differentiated into adipocytes. 2. This expanding population of adipocytes produced an antimicrobial peptide called cathelicidin, which targeted the bacteria. Evidence Rating Level: 2 (Good) Study Rundown: The skin represents an essential component of the innate...
1. Once-weekly dalbavancin was not inferior to twice-daily vancomycin and linezolid in treating acute bacterial skin infection. 2. Fewer adverse events were reported in patients treated with dalbavancin compared to those treated with vancomycin and linezolid.  Evidence Rating Level: 1 (Excellent)        Study Rundown: Cellulitis, an infection of the skin...
Image: PD 1. An investigational S. aureus vaccine, V710, was shown to not decrease incidence of postoperative infection in patients undergoing cardiothoracic surgery with median sternotomy.   2. Among patients with postoperative S. aureus infection, V710 vaccination is associated with increased rates of multiorgan failure and mortality.   Study Rundown: The median sternotomy serves...