Risk of myopathy and myalgia among statin users may be small and clinically insignificant
1. 27.1% of patient in the statin group reported muscle pain and weakness compared to 26.6% in the control groups. ...
Tag: statin therapy
Statin use provide effective primary prevention against cardiovascular disease in high-risk patients – US Preventive Services Task Force
1. Statin use in patients at increased risk of cardiovascular disease without prior history of cardiovascular disease events was significantly ...
Systematic review and meta-analysis of statin-induced reduction in LDL-C demonstrates modest absolute benefits
1. This systematic review and meta-analysis found a modest absolute risk reduction of 0.8% in all-cause mortality from statin-induced therapy ...
Combination-drug therapy and earlier detection recommended to improve outcomes in heterozygous familial hypercholesterolemia
1. A significantly greater proportion of patients receiving 2-3 lipid lowering medications achieved LDL-cholesterol targets compared to those receiving monotherapy. ...
Statin therapy initiation is associated with diabetes progression
1. A group of patients who newly initiated statins, compared to one that newly initiated another type of type 2 ...
Discontinuation of statins in older patients with polypharmacy associated with increased cardiovascular events
1. Older patients with polypharmacy who discontinued statins had increased rates of admissions for heart failure, all-cause emergency hospital admissions, ...
LDL cholesterol-lowering therapies reduce the risk of cardiovascular events in older patients
1. In patients aged ≥75 years, LDL cholesterol-lowering therapies reduced the risk for major vascular events, including cardiovascular death, myocardial ...
Early myocardial infarction and familial hypercholesterolemia
1. In this retrospective cohort study of adults under age 50 with myocardial infarction, 9% met criteria for definite or ...