Tag: statin

1. The standardized Ready to Reduce Risk (3R) program resulted in improvements to lifestyle among those taking medication for prevention of cardiovascular disease. 2. 3R did not improve medication adherence compared to the control group. Evidence Rating Level: 2 (Good) Nearly one-third of deaths across the globe are attributable to cardiovascular disease...

1. Targeting a lower LDL does not impact carotid plaque incidence but does increase the rate of regression of pre-existing atherosclerotic lesions among patients who have experienced an ischemic stroke. Evidence Rating Level: 2 (Good) Low-density lipoprotein (LDL) is a lipid molecule that has been implicated in the development of atherosclerotic...

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1. Incidence of intracerebral hemorrhage in older patients has increased since 1948. 2. Hypertension and statin use are both associated with intracerebral hemorrhage. Evidence Rating Level: 3 (Average) Study Rundown: Of all stroke types, intracerebral hemorrhage (ICH) possesses the highest mortality rate and is the greatest cause of disability. While stroke incidence...

1. This randomized controlled trial showed that patients with ischemic stroke or transient ischemic attack with target LDL levels of less than 70 mg/dL had lower rates of subsequent cardiovascular events when compared to target LDL levels of 90 to 110 mg/dL.  2. Patients were provided with a statin and...

1. This randomized controlled trial showed that patients with ischemic stroke or transient ischemic attack with target LDL levels of less than 70 mg/dL had lower rates of subsequent cardiovascular events when compared to target LDL levels of 90 to 110 mg/dL.  2. Patients were provided with a statin and...

Identification of patients and plaques vulnerable to future coronary events with near-infrared spectroscopy intravascular ultrasound imaging: a prospective, cohort study 1. NIRS imaging in patients undergoing cardiac catheterization for suspected coronary artery disease can be used in identifying high-risk non-culprit lesions contributing to future major adverse coronary events.  Evidence Rating Level:...

The risk of adverse cardiovascular outcomes in patients hospitalized with acute coronary syndrome (ACS) is highest in elderly patients. Although recent clinical trials have shown that high-intensity statin therapy significantly reduces adverse cardiovascular events for patients with established coronary heart disease, its use in elderly individuals remains controversial. As...

1. In this case report, two patients who developed statin-associated autoimmune myopathy had their cholesterol levels effectively managed with the novel cholesterol reduction medication evolocumab. 2. The use of this drug did not result in any adverse events for the two patients included in the case study throughout follow-up. Evidence...

1. This study showed that the net benefit of statins compared to risk varied considerably with respect to the age of the patient, patient sex and the type of statin utilized. 2. This modeling study suggested that statins may be overprescribed even among at-risk patients. Evidence Rating Level: 3 (average) Study Rundown:...