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Risk of myopathy and myalgia among statin users may be small and clinically insignificant
1. 27.1% of patient in the statin group reported muscle pain and weakness compared to 26.6% in the control groups. ...
Tag: statin
Moderate-intensity statin plus ezetimibe is non-inferior to high-intensity statin monotherapy
1. 3-year composite outcome of stroke and cardiovascular disease was comparable between both groups (9.1% combination vs. 9.9% monotherapy). 2. ...
Systematic review and meta-analysis of statin-induced reduction in LDL-C demonstrates modest absolute benefits
1. This systematic review and meta-analysis found a modest absolute risk reduction of 0.8% in all-cause mortality from statin-induced therapy ...
Combination-drug therapy and earlier detection recommended to improve outcomes in heterozygous familial hypercholesterolemia
1. A significantly greater proportion of patients receiving 2-3 lipid lowering medications achieved LDL-cholesterol targets compared to those receiving monotherapy. ...
Comparing incidence and severity of COVID-19 between statin users and non-users
1. Comparing statin and non statin using patients, there is no difference in rates of positive COVID-19 test result. 2. ...
Statin therapy initiation is associated with diabetes progression
1. A group of patients who newly initiated statins, compared to one that newly initiated another type of type 2 ...
Discontinuation of statins in older patients with polypharmacy associated with increased cardiovascular events
1. Older patients with polypharmacy who discontinued statins had increased rates of admissions for heart failure, all-cause emergency hospital admissions, ...
Rosuvastatin therapy for people with HIV not associated with decreased biomarkers of inflammation and immune activation
1. Among virologically suppressed persons with HIV at moderate risk of cardiovascular disease, daily administration of rosuvastatin did not lead ...
Colchicine may lower the risk of cardiovascular events in patients with coronary disease
1. Patients who received low-dose colchicine daily had a ~30% lower risk of cardiovascular events compared to those who received ...
Effectiveness of the ready to reduce risk (3r) complex intervention for the primary prevention of cardiovascular disease
1. The standardized Ready to Reduce Risk (3R) program resulted in improvements to lifestyle among those taking medication for prevention ...
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